Antibacterial efficacy of intracanal medicaments on bacterial biofilm: a critical review

Authors

  • Carlos Estrela Federal University of Goiás; Department of Oral Science
  • Gilson Blitzkow Sydney Federal University of Paraná; Department of Endodontics
  • José Antonio Poli Figueiredo Pontifical Catholic University of Rio Grande do Sul
  • Cyntia Rodrigues de Araújo Estrela Federal University of Goiás; Biological Science Institute

DOI:

https://doi.org/10.1590/S1678-77572009000100002

Keywords:

Biofilm, Intracanal medicaments, Antimicrobial efficacy

Abstract

The purpose of this paper is to discuss critically the antibacterial efficacy of intracanal medicaments on bacterial biofilm. Longitudinal studies were evaluated by a systematic review of English-language articles retrieved from electronic biomedical journal databases (MEDLINE, EMBASE, CENTRAL) and handsearching records, using different matches of keywords for root canal biofilm, between 1966 and August 1st, 2007. The selected articles were identified from titles, abstracts and full-text articles by two independent reviewers, considering the tabulated inclusion and exclusion criteria. Disagreements were resolved by consensus. The search retrieved 91 related articles, of which 8.8% referred to in vivo studies demonstrating the lack of efficacy of endodontic therapy on bacterial biofilm. Intracanal medicaments were found to have a limited action against bacterial biofilm.

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Published

2009-02-01

Issue

Section

Review

How to Cite

Antibacterial efficacy of intracanal medicaments on bacterial biofilm: a critical review . (2009). Journal of Applied Oral Science, 17(1), 1-7. https://doi.org/10.1590/S1678-77572009000100002