Physiological determinants of weight and appetite control

Authors

  • Zuleika S. C. Halpern Universidade de São Paulo; Faculdade de Medicina; Hospital das Clínicas; Instituto de Psiquiatria
  • Mariana Del Bosco Rodrigues Universidade de São Paulo; Faculdade de Medicina; Hospital das Clínicas; Instituto de Psiquiatria
  • Roberto Fernandes da Costa Universidade de São Paulo; Faculdade de Medicina; Hospital das Clínicas; Instituto de Psiquiatria

DOI:

https://doi.org/10.1590/S0101-60832004000400002

Keywords:

Obesity, weight control, satiety and appetite

Abstract

Obesity is currently one of the main problems of public health, presenting multifactorial etiology. The main involved factors in the control of weight and appetite are neuronal, endocrine, adipocity and intestinal. Leptine and insuline are hormones produced proportionally to adipose mass and act stimulating the catabolism. In the central nervous system, insuline and leptine interact with hypothalamic receivers favoring the satiety. Individuals with obesity have high seric concentrations of these hormones and present resistance to their action. The intestinal peptides, associated with other signals, can stimulate (greline and orexine) or inhibit (CKK, leptine and oxymodulin) the food intake. All act in the hypothalamic centers, that are the major responsible for the nutrititional behavior.

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Published

2004-01-01

Issue

Vol. 31 No. 4 (2004)

Section

Original Articles

License

Once accepted for publication, the manuscript becomes permanent property of the Archives of Clinical Psychiatry. This copyright transfer subsumes exclusive and unlimited entitlement of the Archives of Clinical Psychiatry to publish and distribute the full contents of articles in whichever publishing medium, including press and electronic media, in Brazil and abroad.

Manuscripts are accepted with the understanding that the Editor and the editorial staff have the right to make revisions aimed at greater conciseness, clarity, and conformity with Journal style, of course without changing its content.

How to Cite

Physiological determinants of weight and appetite control . (2004). Archives of Clinical Psychiatry, 31(4), 150-153. https://doi.org/10.1590/S0101-60832004000400002