New antipsychotics for the treatment of schizophrenia

Authors

  • Hélio Elkis International Psychopharmacology Algorithm Project
  • Mário Rodrigues Louzã Universidade de Würzburg

DOI:

https://doi.org/10.1590/S0101-60832007000800009

Keywords:

Antipsychotics, neuroleptics, asenapine, ACP-103, bifeprunox, paliperidone, long acting injectable risperidone, sertindole

Abstract

BACKGROUND: The second generation antipsychotics represent the great achievement in the treatment of schizophrenia of the last decades. However in the last years some new antipsychotics were synthesized and such new compounds may represent great perspectives for the field of the treatment of schizophrenia. Some of these compounds are in use while others are still on evaluation through clinical trials. OBJECTIVE: Summarize the current knowledge of new antipsychotics. METHODS: PubMed search as well literature provided by the manufactures. RESULTS AND CONCLUSIONS: We present the main pharmacological characteristics as well as profiles of efficacy, security and tolerability of the following compounds: Asenapine, ACP-103, Bifeprunox, Paliperidone, Long Acting Injectable Risperidone and Sertindole.

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Published

2007-01-01

Issue

Section

Reviews of Literature

How to Cite

New antipsychotics for the treatment of schizophrenia . (2007). Archives of Clinical Psychiatry, 34(supl.2), 193-197. https://doi.org/10.1590/S0101-60832007000800009