Fetus in Fetu as a suprarenal mass in a neonate – a rare and perplexing entity
DOI:
https://doi.org/10.4322/acr.2021.347Keywords:
Biopsy, fine needle, Adrenal Glands, Teratoma, FetusAbstract
Fetus in fetu (FIF) is a rare entity in which a malformed vertebrate fetus is incorporated within its twin. This entity should be differentiated from a teratoma, which has more malignant potential. We describe a neonate with a heterogeneous calcified suprarenal mass. The aspiration cytology revealed a heterogeneous cell population with spindle cells and small round blue cells. Operative and histopathologic examination showed features consistent with a fetus in fetu. This case report describes a rare entity and discusses its clinical presentation, cytological features on fine-needle aspiration, and the difficulties posed in its differentiation from a teratoma.
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Grant P, Pearn JH. Fetus-in-foetu. Med J Aust. 1969;1(20):1016-9. http://dx.doi.org/10.5694/j.1326-5377.1969.tb49866.x. PMid:5815070.
Sharma A, Goyal A, Sharma S. Fetus in fetu: a rare case report. J Res Med Sci. 2012;17(5):491-4. PMid:23626618.
Brand A, Alves MC, Saraiva C, et al. Fetus in fetu--diagnostic criteria and differential diagnosis--a case report and literature review. J Pediatr Surg. 2004;39(4):616-8. http://dx.doi.org/10.1016/j.jpedsurg.2003.12.029. PMid:15065040.
Hoeffel CC, Nguyen KQ, Phan HT, et al. Fetus in fetu: a case report and literature review. Pediatrics. 2000;105(6):1335-44. http://dx.doi.org/10.1542/peds.105.6.1335. PMid:10835078.
Ji Y, Chen S, Zhong L, et al. Fetus in fetu: two case reports and literature review. BMC Pediatr. 2014;14(1):88. http://dx.doi.org/10.1186/1471-2431-14-88. PMid:24693883.
Cingel V, Durdik S, Babala J, Polak S, Varga I. Fetus in fetu from newborn’s mediastinum: case report and a review of literature. Surg Radiol Anat SRA. 2012;34(3):197-202. http://dx.doi.org/10.1007/s00276-011-0868-9. PMid:21901374.
Spencer R. Parasitic conjoined twins: external, internal (fetuses in fetu and teratomas), and detached (acardiacs). Clin Anat. 2001;14(6):428-44. http://dx.doi.org/10.1002/ca.1079. PMid:11754238.
Ji Y, Song B, Chen S, et al. Fetus in fetu in the scrotal sac: case report and literature review. Medicine. 2015;94(32):e1322. http://dx.doi.org/10.1097/MD.0000000000001322. PMid:26266375.
Hopkins KL, Dickson PK, Ball TI, Ricketts RR, O’Shea PA, Abramowsky CR. Fetus-in-fetu with malignant recurrence. J Pediatr Surg. 1997;32(10):1476-9. http://dx.doi.org/10.1016/S0022-3468(97)90567-4. PMid:9349774.
Varga I, Jablonska V, Cingel V, Kubikova E, Dorko F, Polak S. The first histological and immunohistochemical examination of thymus in a case of fetus in fetu. Ann Anat. 2010;192(4):232-6. http://dx.doi.org/10.1016/j.aanat.2010.05.007. PMid:20634048.
Sharmal S, Mishra K. Limitations in the diagnosis of childhood teratoid lesions on fine needle aspiration cytology. Acta Cytol. 2010;54(2):142-7. http://dx.doi.org/10.1159/000324999. PMid:20391969.
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