Encapsulation of flaxseed oil extract in alginate–salep system by ionic gelation

Authors

  • Zam Wissam Al-Andalus University for Medical University, Faculty of Pharmacy, Department of Analytical and Food Chemistry https://orcid.org/0000-0002-2733-1884
  • Housheh Samer Al-Andalus University for Medical University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry and Quality Control

DOI:

https://doi.org/10.1590/s2175-97902019000200261

Keywords:

Flaxseed oil, Sodium alginate, Salep, Beads

Abstract

The objective of the current study was to encapsulate flaxseed oil extracted from finely grounded flaxseed powder and determined for its fatty acids content by GC/FID. Ionotropic gelation method was used to form beads containing 40% flaxseed oil with vitamin E being used as an antioxidant agent. The study employed calcium chloride solution as crosslinking agent with a combination of sodium alginate and salep. The effect of polymer concentrations and calcium chloride concentration on the morphology, entrapment efficiency and oil release was studied. The encapsulation efficiency reached 93.46 ± 0.064% using 0.6% of salep and 2% sodium alginate with 0.3M calcium chloride gelling solution. In SGF medium, the matrix released only about 28.56% of the entrapped flaxseed oil after 2 hours. The rest of the oil then released in the SIF medium, continuing for up to 5 h to release 99.32% of the oil.

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Published

2019-12-09

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Article

How to Cite

Encapsulation of flaxseed oil extract in alginate–salep system by ionic gelation. (2019). Brazilian Journal of Pharmaceutical Sciences, 55, e00261. https://doi.org/10.1590/s2175-97902019000200261