Profile of drugs used by university students for self-medication in times of the COVID-19 pandemic
A scoping review
DOI:
https://doi.org/10.1590/Palavras-chave:
Review, Students, Self-Medication, COVID-19, Drug UtilizationResumo
A significant increase in self-medication was observed during the SARS-CoV-2 pandemic, especially among university students due to their higher level of knowledge and awareness, making them more prone to self-medication. Therefore, in this scoping review we aimed to understand the profile of medications used for self-medication among university students during the pandemic, both for COVID-19 prevention and other reasons. We followed the PRISMA-ScR guidelines in conducting the review. The PICo guiding question was, “What is the profile of medications used for self-medication during the COVID-19 pandemic among university students?” Searches were conducted in the Scielo, PubMed, Embase, EBSCOhost, Web of Science, Scopus, BVS, Google Scholar, and CAPES databases based on MESH and DeCS descriptors. A total of 35 studies were selected, with eight (22.8%) reporting self-medication for COVID-19 prevention/treatment ranging from 14-83%, four (11.4%) reporting self-medication for specific symptoms ranging from 11-95%, 19 (54.4%) reporting several reasons for students self-medicating with a range of 50-100%, and four (11.4%) studies not specifying the reason for medication use in self-medication varying from 3-93%. The included studies revealed that the irrational use of medications is a common practice among university students, with varied prevalence of self-medication observed in this population during the COVID-19 pandemic.
Downloads
Referências
Alahendra AMAAU, Pereira OTS, Guruge ML, Anthony DK, Dasanayaka C, Wijekoon WMPDS. Perceived Self- medication Practices and Associated Factors among Undergraduates in a Non-State University. 2021. SLIIT J Humanit Sci. 2021;2(1):29-47.
Albuquerque AV, Tavares DPS, Silva LB, Marques RAC, Almeida ACG. Estratégias associadas à prevenção da resistência de antimicrobianos no âmbito hospitalar: Revisão sistemática. Res, Soc Development. 2022;11(7): 23811729990.
Alduraibi RK, Altowayan WM. A cross-sectional survey: knowledge, attitudes, and practices of self-medication in medical and pharmacy students. BMC Health Serv Res. 2022;22(1):352.
Alhaj HHM, Al-lahawi AMB, Al-abeed M, Omer MEA, F. Abubakar Y. Misuse of antibiotic among university and higher education students in Sudan a cross-sectional. 2021. PREPRINT (Version 1) available at Research Square. 2021.
Al-Qahtani AM, Shaikh IA, Shaikh MAK, Mannasaheb BA, Al-Qahtani FS. Prevalence, perception, and practice, and attitudes towards self-medication among undergraduate medical students of Najran University, Saudi Arabia: A cross-sectional study. Risk Manag Healthc Policy. 2022;16(15):257-276.
Alshammari F, Alobaida A, Alshammari A, Alharbi A, Alrashidi A, Almansour A, et al. University Students’ Self-Medication Practices and Pharmacists’ Role: A Cross- Sectional Survey in Hail, Saudi Arabia. Front Public Health. 2021;17(9):779107.
Alves MCGS. Avaliação da prática de automedicação por alunos do curso de Saúde Coletiva da Universidade Federal do Sul e Sudeste do Pará durante a pandemia de COVID-19. [Trabalho de Conclusão de Curso].Marabá: Universidade Federal do Sul e Sudeste do Pará, Faculdade de Saúde Coletiva,2022.
Andrade EA, Moreno VG, Ortiz M. Perfil de uso de medicamentos e automedicação, em uma população universitária, frente à pandemia da Covid-19 / Profile of use of medicines and self-medication, in a university population, in front of Covid-19 pandemic. Braz J Dev. 2021;7(7):73772-73784.
Armillo CM, Corsiga AJS, Enriquez RMG, Libang JD, Lucban JMP, Roxas MAM, et al. Level of self- medication awareness to internet usage among selected, non-medical students in Centro Escolar university-Manila during COVID-19 pandemic. GSC Biol Pharm Sci. 2022;20(02):152-163.
Behzadifar M, Behzadifar M, Aryankhesal A, Ravaghi H, Baradaran HR, Sajadi HS, et al. Prevalence of self-medication in university students: systematic review and meta-analysis. East Mediterr Health J. 2020;26(7):846- 857.
Bello IB, Akinnawo EO, Akpunne BC, Egbunu. Knowledge of COVID-19 and preventive measures on self-medication practices among Nigerian undergraduates. Cogent Arts Humanities. 2022;9:2049480.
Brasil. Ministério da Saúde. Manejo terapêutico da Síndrome Gripal na APS. [Internet] Brasília (DF): Ministério da Saúde, 2020a. [cited 2022 dec 13]. Available from: Available from: https://saude.rs.gov.br/upload/arquivos/202004/14140606-4-ms-protocolomanejo-aps-ver07abril.pdf
» https://saude.rs.gov.br/upload/arquivos/202004/14140606-4-ms-protocolomanejo-aps-ver07abril.pdf
Brasil. Ministério da Saúde. Uso racional de medicamentos. [Internet] Brasília (DF): Ministério da Saúde , 2013. [cited 2022 dec 15]. Available from: Available from: https://www.gov.br/saude/pt-br/composicao/sctie/daf/uso-racional-de-medicamentos
» https://www.gov.br/saude/pt-br/composicao/sctie/daf/uso-racional-de-medicamentos
Brasil. Ministério da Saúde.Cuidado com as Fake News. [Internet] Brasília (DF): Ministério da Saúde , 2020b. [cited 2022 dec 13]. Available from: Available from: https://coronavirus.rs.gov.br/cuidado-com-as-fake-news
» https://coronavirus.rs.gov.br/cuidado-com-as-fake-news
JCM, Lima WG, Cardoso BG, Simião DC, Amorim JM, Silva CA. Uso irracional de medicamentos e plantas medicinais contra a COVID-19 (SARS-CoV-2): um problema emergente. Brazilian J H Pharm. 2020;2(3):37-53. [cited 2022 dec 13] Available from: Available from: https://revistacientifica.crfmg.emnuvens.com.br/crfmg/article/view/102/66
» https://revistacientifica.crfmg.emnuvens.com.br/crfmg/article/view/102/66
Cândido RCF, Perini E, Pádua CMD, Junqueira DR. Prevalência e fatores associados ao uso de metilfenidato para neuroaprimoramento farmacológico entre estudantes universitários. Einstein (São Paulo). 2019;18:eAO4745.
Cienfuegos B, Alexandre C, Falla C, Claudia A. Factores relacionados con la automedicación en estudiantes de Medicina Humana de la Universidad Señor de Sipán. [Tesi el título profesional de médico cirujano]. Perú: Universidad Señor de Sipán, 2022.
Conselho Federal de Farmácia (CFF). Venda de Medicamentos Psiquiátricos cresce na pandemia. [cited 2022 dec 09]. Available from: Available from: https://cff.org.br/noticia.php?id=6015
» https://cff.org.br/noticia.php?id=6015
Cvitković M. Use of antidepressants in the student population. [Tese] .Zagreb:Faculty of Pharmacy and Biochemistry;University of Zagreb, 2021.
Dantas FSE, Coutinho VEA, de Abreu Carolino R, Sarmento TDAB, da Cunha CVL, da Silva, CP, Ferreira ML. Automedicação no contexto de COVID-19, os perigos da prática e fatores associados. Res, Soc Dev. 2023;12(6):e11912642039-e11912642039.
Escobar LE, Villanueva CAB, Corales RV, Palacios MIP, Reyes MAV. Factores relacionados con la automedicación en estudiantes de ciencias de la salud. Universidad y Sociedad. [cited 2022 dec 09].2022;14(3):460-8. Available from: Available from: https://rus.ucf.edu.cu/index.php/rus/article/view/2886
» https://rus.ucf.edu.cu/index.php/rus/article/view/2886
Elayeh E, Akour A, Haddadin RN. Prevalence and predictors of self-medication drugs to prevent or treat COVID-19: Experience from a Middle Eastern country. International journal of clinical practice. 2021;75(11):e14860.
Fallah G, Moudi S, Hamidia A, Bijani A. Stimulant use in medical students and residents requires more careful attention. Caspian J Intern Med. 2018;9(1):87-91.
Faria LB, Costa ACC, Costa CCF, Silva FC, Ribeiro GR. Automedicação entre os estudantes de medicina de uma instituição de ensino superior de Anápolis- GO. [Trabalho de curso]. Anápolis: Universitário Centro de Anápolis, Unievangélica, 2020.
Fetensa G, Tolossa T, Etafa W, Fekadu G. Prevalence and predictors of self-medication among university students in Ethiopia: a systematic review and meta-analysis. J Pharm Policy Pract. 2021;14,107.
Food and Drug Administration (FDA). Atualização sobre o coronavírus (COVID-19): FDA adverte o vendedor que comercializa produtos perigosos de dióxido de cloro que alegam tratar ou prevenir COVID-19. 2020. [cited 2022 dec 09]. Available from: Available from: https://www.fda.gov/news-events/press-announcements/coronavirus-covid-19-update-fda-warns-seller-marketing-dangerous-chlorine-dioxide-products-claim
Fundação Oswaldo Cruz (Fiocruz). Ministério da saúde. (Brasil). Antibióticos: resistência de microrganismos é grave ameaça à saúde global. [Internet] Brasília (DF): Ministério da Saúde , 2019. [cited 2022 dec 14]. Available from:Available from:https://portal.fiocruz.br/noticia/antibioticos-resistencia-de-microrganismos-e-grave-ameaca-saude-global
González GM, Guitiérrez MLY, Estrada KR, Santiago OG. Automedicación para la prevención del covid-19 en estudiantes universitarios del noreste de méxico. Interciencia. 2022;47(6):0378-1844.
Grigoryan L, Haaijer-Ruskamp FM, Burgerhof JG, Mechtler R, Deschepper R, Tambic-Andrasevic A, et al. Self-medication with antimicrobial drugs in Europe. Emerg Infect Dis. 2006;12(3):452-9.
Guedes RAC, Álvares ACM. O uso racional de antimicrobianos como prevenção da resistência bacteriana. 2017. [cited 2023 jan 14]. Available from: Available from: http://www.senaaires.com.br/wp-content/uploads/2017/05/o-uso-racional-de-antimicrobianos-como-preven%C3%87%C3%83o-da-resist%C3%8Ancia- bacteriana.pdf
» http://www.senaaires.com.br/wp-content/uploads/2017/05/o-uso-racional-de-antimicrobianos-como-preven%C3%87%C3%83o-da-resist%C3%8Ancia- bacteriana.pdf
Infectious diseases society of America (IDSA). IDSA Guidelines on the Treatment and Management of Patients with COVID-19. 2022. [cited 2022 dec 13]. Available from: Available from: https://www.idsociety.org/practice-guideline/covid-19-guideline-treatment-and-management/#null
» https://www.idsociety.org/practice-guideline/covid-19-guideline-treatment-and-management/#null
Johora F, Abbsy AA, Jeenia FT, Sojib, FA, Sabiha K, Khan MM, et al. Viewpoint Regarding COVID-19 Vaccine and Pursuing Self-medication amidst Medical Students. Int J Pharma Sci Res (IJPSR). 2020;11:0975-9492
Kazemioula G, Golestani S, Alavi SMA, Taheri F, Gheshlagh R, Lotfalizadeh MH. Prevalence of self-medication during the COVID-19 pandemic: A systematic systematic review and meta-analysis. Front. Saúde Pública. 2022;10:1041695.
Lei X, Jiang H, Liu C, Ferrier A, Mugavin J. Self- Medication Practice and Associated Factors among Residents in Wuhan, China. Int J Environ Res Public Health. 2018; 15(1):68.
Lima DS, Guedes JPM. Atribuições do farmacêutico no Uso racional de medicamentos e automedicação. Research, Society and Development. 2021;10(15): 263101522827.
Malik M, Tahir MJ, Jabbar R, Ahmed A, Hussain R. Self- medication during Covid-19 pandemic: challenges and opportunities. Drugs Ther Perspect. 2020; 36(12):565-567.
Mannasaheb BA, Al-Yamani MJ, Alajlan SA, Alqahtani LM, Alsuhimi SE, Almuzaini RI, et al. Knowledge, Attitude, Practices and Viewpoints of Undergraduate University Students towards Self-Medication: An Institution-Based Study in Riyadh. International Journal of Environmental Research and Public Health. 2021 ;18(16):8545.
Marra LP, Oliveira Jr HA, Medeiros FC, Brito GV, Matuoka JY, Parreira PCL, et al. Ivermectina para covid-19. Revisão sistemática rápida. Revisão sistemática rápida. [cited 2022 dec 13]. Available from: Available from: https://oxfordbrazilebm.com/index.php/2020/05/07/ivermectina-para-otratamento-de-pacientes-com-covid-19-revisao-sistematica-rapida2/
Maurício FD. Avaliação da prática de automedicação pelos estudantes da UFCG - Campus Cuité durante a pandemia da Covid - 19. [Trabalho de Conclusão de Curso]. Cuité:Universidade Federal de Campina Grande; 2022.
Melo JR, Duarte EC, Moraes MV, Fleck K, Arrai, PSD. Automedicação e uso indiscriminado de medicamentos durante a pandemia da COVID-19. Cadernos de Saúde Pública, 2021;37(4):00053221.
Mendes GB. Uso racional de medicamentos: o papel fundamental do farmacêutico. Ciênc. Saúde Coletiva 13. 2008;13:569-571.
Miñan-Tapia A, Conde-Escobar A, Calderon-Arce D, Cáceres-Olazo D, Peña-Rios AJ, Donoso-Romero RC. Fatores associados à automedicação com medicamentos relacionados à COVID-19 em estudantes de ciências da saúde de uma cidade peruana [Internet]. Pré-impressões SciELO. 2020 [cited 2022 dec. 09]. Available from: Available from: https://preprints.scielo.org/index.php/scielo/preprint/view/1225
» https://preprints.scielo.org/index.php/scielo/preprint/view/1225
Misli SBM, Yusof AAP, Masri AM, Halimaton T, Kunjukunju A. Knowledge Attitude, and Practice of Undergraduate Nursing Students Regarding Self- Medication. SSRG International Journal of Nursing and Health Science. 2021;7:1-7.
de Moraes LGM, Bernardina LSD, Andriato LC, Dalvi LR, de Sousa Loyola YC. Automedicação em acadêmicos de Medicina. ver Soc Bras Clín Méd. 2018;16(3):167-170.
Mostajo-Radji MA. Pseudoscience in the times of crisis: How and why chlorine dioxide consumption became popular in Latin America during the COVID-19 pandemic. Frontiers in Political Science. 2021;3:25.
Nobre Junior NFN, Andrade LG. Atenção farmacêutica e a promoção do Uso racional de medicamentos . Revista Ibero-Americana de Humanidades, Ciências e Educação. 2022;8(3):1156-1166.
Organização Pan-Americana da Saúde (OPAS). World Health Organization (WHO). La OPS no recomienda tomar productos que contengan dióxido de cloro, clorito de sodio, hipoclorito de sodio o derivados, 16 de julio del 2020. [cited 2022 dec 13]. Available from: Available from: https://iris.paho.org/handle/10665.2/52484
» https://iris.paho.org/handle/10665.2/52484
Okoye OC, Adejumo OA, Opadeyi AO, Madubuko CR, Ntaji M, Okonkwo KC, et al. Self medication practices and its determinants in health care professionals during the coronavirus disease-2019 pandemic: cross-sectional study. Int J Clin Pharm. 2022;44(2):507-516.
Ouzzani M, Hammady H, Fedorowicz Z, Elmagarmid AK. Rayyan-a web and mobile app for systematic reviews. Syst Rev. 2016;5:1-10.
Palikhey A, Shrivastava AK, Shrestha L, Gurung S, Yadav CK, Pandit M, et al. Self-medication Practices among Medical and Non-medical Students of Siddharthanagar, Nepal during COVID-19 Pandemic. Journal of KIST Medical College. 2021;3(6):40-48.
Popp M, Reis S, Schießer S, Hausinger RI, Stegemann M, Metzendorf MI, et al. Ivermectin for preventing and treating COVID-19. Cochrane Database of Systematic Reviews. Cochrane Database of Systematic Reviews 2022, Issue 6. Art. No.: CD015017.
Quincho-Lopez A, Benites-Ibarra CA, Hilario-Gomez MM, Quijano-Escate R, Taype-Rondan A (2021) Self- medication practices to prevent or manage COVID-19: A systematic review. PLOS ONE. 2021;16(11):0259317
Remião, F. O paracetamol e a COVID-19. 2020. Rev. Ciência Elem. 2020, 8(2):023.
Roblero AGT, Toledo AGV, Cruz SY, Díaz CMZ, Sarmiento WZ. Prevalencia del consumo de analgésicos en estudiantes de medicina durante las clases virtuales enero - junio 2022. AMU. 2022;1(02):117-28.
Rojas-Miliano C, Caseres DNG, Zárate-Vargas AM, Araujo-Ramos G, Rosales-Guerra, J, Quiñones- Laveriano DM. Características y factores asociados a la automedicación por COVID-19 en estudiantes de una universidad peruana. Revista Cubana de Farmacia. 2022;55(1):712.
Saleem RT, Butt MH, Ahmad A, Amin M, Amir A, Ahsan A et al. Practices and Attitude of Self-medication during COVID-19 Pandemic in University Students with Interventional Role of Pharmacist: a Regional Analysis 2021. Revista Latino-Americana de Farmácia. 2021;40(8):1946-53.
Santos ELG, Pereira LLP, Seabra ADBMH, Fonseca, AA, Freitas TF, Pereira, EJ et al. Comportamento de estudantes universitários da área da saúde com relação à utilização de medicamentos e a prática da automedicação. Research, Society and Development . 2022;11(12):130111234353.
Sapana AR, Rodríguez HA, Salcedo VJL, Hernandez LFE, Ancachi CM, Camaticona WL, Huanco DA. Factores asociados a la práctica de automedicación en estudiantes de Medicina. RMB. 2021;15(2):37-49.
Sarango KAR, Siguenza JIT, Unuzungo MZA, Bermeo FIZ. Factores que influyen en la automedicación durante la pandemia en estudiantes universitarios. Revista Estudiantil CEUS. 2020,2:13-18.
Shrestha JTM, Kushwaha DK, Tiwari S, Bhattarai P. Study of Self-medication among First and Seventh Semester Medical and Dental Undergraduate Students of Tertiary Care Teaching Hospital in Nepal: A Descriptive Cross-sectional Study. JNMA J Nepal Med Assoc. 2021;59(233):55-60.
Silva J, Vieira P, Gomes AL, Roth T, Azevedo MHP, Marques DR.Sleep difficulties and use of prescription and non-prescription sleep aids in Portuguese higher education students. Sleep Epidemiology. 2021a;1:100012.
Silva Júnior JGS, Tavares CGS, Monte TVS, Nascimento WM, Oliveira JRS, Callou MAM. Automedicação com antibióticos e suas consequências fisiopatológicas: uma revisão. Rev Rios Saúde. 2018;1:1.
Silva VMP, Oliveira HJP, Souza WK, Souza DM, Santana JAR , Canejo SP, et al. Perfil epidemiológico do uso de medicamentos entre estudantes universitários. REAS. 2021b;13(10):9030.
Sljivo A, Smailbegovic FG, Mulać A, Dadic I, Kubat A, Sirucic I. Mental Health and Substance Abuse Among the Bosnia and Herzegovina Student Population During the COVID-19 Outbreak. Mater Sociomed. 2022;34(1):8-13.
Soriano-Moreno DR, Fernandez-Guzman D, Ccami-Bernal F, Rojas-Miliano C, Nieto-Gutierrez W. Factors associated with the consumption of chlorine dioxide to prevent and treat COVID-19 in the Peruvian population: a cross- sectional study. BMC Public Health. 2021;21(1):2109.
Souza KB. Avaliação e fatores associados à prática de automedicação para prevenção ou tratamento de covid-19 na população universitária do sul do brasil. [Dissertação]. Rio Grande: Universidade Federal do Rio Grande; 2022.
Souza MNC, Ricardino IEF, Sampaio K, Silva MR, Lima APG, Fernandes DL, et al. Ocorrência de Automedicação na população Brasileira como estratégia preventiva ao SARS-CoV-2. Research, Society and Development . 2021;10(1):44510111933.
Subedi C. Self-Medication Practices in Pokhara: A Study of Knowledge and Purpose among Non-Medical Students. Prithvi J Res Innov. 2021;3(1):52-60.
Tavares BLC, Gomes LES. Uso indiscriminado de medicamentos e automedicação no Brasil. Centro de Informações de Medicamentos (CIM). Universidade Federal da Paraíba (UFPB). 2020 [cited 2022 dec.15]. Available from: Available from: https://www.ufpb.br/cim/contents/menu/publicacoes/cimforma/uso-indiscriminado-de-medicamentos-e-automedicacao-no-brasil
Tricco AC, Lillie E, Zarin W, O’Brien KK, Colquhoun H, Levac D, et al. PRISMA extension for scoping reviews (PRISMA-ScR): checklist and explanation. Ann Intern Med. 2018;169(7):467-473.
Tritany RF, Tritany EF. Uso racional de medicamentos para COVID-19 na Atenção Primária à Saúde. Saúde em Redes. 2020;6(2).
Wegbom AI, Edet CK, Raimi O, Fagbamigbe AF, Kiri VA . Self-medication practices and associated factors in the prevention and/or treatment of COVID-19 virus: a population-based survey in Nigeria. Front Public Health . 2021:(9);606801.
Witteveen, LA. Non-medical use of ADHD prescription drugs among US college students at a public research university in a small rural town. Honors College Theses 672; 2021. [cited 2023 jan.15]. Available from: Available from: https://digitalcommons.georgiasouthern.edu/honors-theses/672/
» https://digitalcommons.georgiasouthern.edu/honors-theses/672/
Wong A. COVID-19 e toxicidade de tratamentos potenciais: Panaceia ou veneno. Emerg Med Australas. 2020;32(4):697-699.
World Health Organization (WHO). Promoting rational use of medicines: core components. World Health Organization. 2002. [cited 2023 jan.15]. Available from: Available from: https://apps.who.int/iris/handle/10665/67438
» https://apps.who.int/iris/handle/10665/67438
World Health Organization (WHO). Therapeutics and COVID-19: living guideline. 2022. [Internet] [cited 2022 dec 13]. Available from: Available from: https://www.who.int/publications/i/item/WHO-2019-nCoV-therapeutics-2022.4
» https://www.who.int/publications/i/item/WHO-2019-nCoV-therapeutics-2022.4
Yasmin F, Asghar MS, Naeem U, Najeeb H, Nauman H, Ahsan MN, et al. Self-Medication Practices in Medical Students During the COVID-19 Pandemic: A Cross-Sectional Analysis. Front Public Health . 2022;9(10):803937.
Yousaf MA, Zahid H, Khalid Z, Khan AT-A, Noreen M, Saleem T, et al. Knowledge, attitude and practices of university students of pakistan towards antibiotic use and resistance: Questionnaire based assessment. BioScientific Review. 2021;3(3):63-82.
Zeb S, Mushtaq M, Ahmad M, Saleem W, Rabaan AA, Naqvi BSZ, et al. Self-Medication as an Important Risk Factor for Antibiotic Resistance: A Multi- Institutional Survey among Students. Antibiotics (Basel). 2022;11(7):842.
Downloads
Publicado
Edição
Seção
Licença
Direitos autorais (c) 2025 Brazilian Journal of Pharmaceutical Sciences

Este trabalho está licenciado sob uma licença Creative Commons Attribution 4.0 International License.
All content of the journal, except where identified, is licensed under a Creative Commons attribution-type BY.
The on-line journal has open and free access.