O impacto de um protocolo de mobilização precoce, viável e de baixo custo em pacientes críticos: comparação com a fisioterapia convencional
DOI:
https://doi.org/10.1590/Palavras-chave:
Mobilização Precoce, Custo, Fisioterapia, Tecnologia de Baixo Custo, Unidade de Terapia IntensivaResumo
Neste estudo foi analisado o resultado da
aplicação de um protocolo de mobilização precoce,
fazendo uso de intervenções de baixo custo, com o
mínimo de equipamentos necessários em uma unidade
de terapia intensiva. Trata-se de um ensaio clínico,
controlado e randomizado, realizado em parceria com
o Laboratório de Avaliação e Pesquisa do Desempenho
Cardiorrespiratório do Departamento de Fisioterapia da
Universidade Federal de Minas Gerais e com a Unidade
de Terapia Intensiva (UTI) do Hospital Risoleta Tolentino
Neves, em Belo Horizonte, Brasil, no período de cinco
meses. Os pacientes foram distribuídos de forma aleatória
em dois grupos (tratamento [GT] n=67 e controle [CG]
n=67). O desfecho primário foram os dias de saída do
leito, enquanto os desfechos secundários foram: tempo
de internação na UTI, tempo de internação hospitalar,
custos de internação, tempo em Ventilação Mecânica
Invasiva (VMI), mortalidade na UTI e mortalidade
hospitalar. As características dos grupos foram similares
na avaliação inicial. Verificou-se que 61 pacientes (97%) do
GT foram retirados do leito, em comparação com apenas
dois pacientes (3%) do GC. O protocolo de mobilização
proposto reduziu os custos de internação em 30,27%,
diferença aproximada de R$7 mil por paciente. A média
de tempo de estadia na UTI do GT foi menor do que a
do GC. Não houve diferença estatisticamente significativa
quanto às horas de permanência em UTI, tempo de
permanência hospitalar e tempo de VMI. A aplicação do
protocolo de mobilização precoce de baixo custo e com
o mínimo de equipamentos foi segura e eficaz para os
pacientes, promovendo a saída precoce do leito.
Downloads
Referências
McIlroy PA, King RS, Garrouste-Orgeas M, Tabah A, Ramanan
M. The effect of ICU diaries on psychological outcomes and
quality of life of survivors of critical illness and their relatives:
a systematic review and meta-analysis. Crit Care Med.
;47(2):273-9. doi: 10.1097/CCM.0000000000003547
Hiser S, Fatima A, Ali M, Needham DM. Post-intensive care
syndrome (PICS): recent updates. J Intens Care. 202323;11(1).
doi: 10.1186/s40560-023-00670-7
Kamdar BB, Sepulveda KA, Chong A, Lord RK, Dinglas VD,
et al. Return to work and lost earnings after acute respiratory
distress syndrome: a 5-year prospective, longitudinal study of
long-term survivors. Thorax. 201716;73(2):125-33. doi: 10.1136/
thoraxjnl-2017-210217
Yende S, Austin S, Rhodes A, Finfer S, Opal S, et al. Long-term
quality of life among survivors of severe sepsis. Crit Care Med.
;44(8):1461-7. doi: 10.1097/CCM.0000000000001658
Dinglas VD, Aronson Friedman L, Colantuoni E, Mendez-Tellez
PA, Shanholtz CB, et al. Muscle weakness and 5-year survival in
acute respiratory distress syndrome survivors. Crit Care Med.
;45(3):446-53. doi: 10.1097/CCM.0000000000002208
Voiriot G, Oualha M, Pierre A, Salmon-Gandonnière C, Gaudet A,
et al. Chronic critical illness and post-intensive care syndrome:
from pathophysiology to clinical challenges. Ann Intens Care.
;12(1). doi: 10.1186/s13613-022-01038-0
Poulsen JB, Møller K, Kehlet H, Perner A. Long-term physical
outcome in patients with septic shock. Acta Anaesthesiol Scan.
;53(6):724-30. doi: 10.1111/j.1399-6576.2009.01921.x
The TEAM Study Investigators and the ANZICS Clinical Trials
Group. Early active mobilization during mechanical ventilation
in the ICU. N Eng J Med. 2022; 387(19):1747-58. doi: 10.1056/
NEJMoa2209083
Wang DS, Moitra VK, Flynn BC. Early mobilization in the
intensive care unit: to rest or to test? J Cardiothor Vasc Anesth.
;37(6):854-6. doi: 10.1053/j.jvca.2023.02.004
Parry SM, Berney S, Warrillow S, El-Ansary D, Bryant AL, et al.
Functional electrical stimulation with cycling in the critically ill:
A pilot case-matched control study. J Crit Care. 2014;29(4):695.
e1-7. doi: 10.1016/j.jcrc.2014.03.017
Segers J, Hermans G, Bruyninckx F, Meyfroidt G, Langer D,
et al. Feasibility of neuromuscular electrical stimulation in
critically ill patients. J Crit Care. 2014;29(6):1082-8. doi: 10.1016/j.
jcrc.2014.06.024
Zayed Y, Kheiri B, Barbarawi M, Chahine A, Rashdan L, et al.
Effects of neuromuscular electrical stimulation in critically ill
patients: A systematic review and meta-analysis of randomised controlled trials. Aust Crit Care. 2020;33(2):203-10. doi: 10.1016/j.
aucc.2019.04.003
Lord RK, Mayhew CR, Korupolu R, Mantheiy EC, Friedman
MA, et al. ICU early physical rehabilitation programs: financial
modeling of cost savings. Crit Care Med. 2013;41(3):717-24. doi:
1097/CCM.0b013e3182711de2
Morris PE, Goad A, Thompson C, Taylor K, Harry B, et al. Early
intensive care unit mobility therapy in the treatment of acute
respiratory failure. Crit Care Med. 2008;36(8):2238-43. doi:
1097/CCM.0b013e318180b90e
Schujmann DS, Teixeira Gomes T, Lunardi AC, Zoccoler Lamano
M, Fragoso A, et al. Impact of a progressive mobility program
on the functional status, respiratory, and muscular systems
of ICU patients. Crit Care Med. 2020;48(4):491-7. doi: 10.1097/
CCM.0000000000004181
Martínez-Velilla N, Casas-Herrero A, Zambom-Ferraresi F,
Sáez de Asteasu ML, et al. Effect of exercise intervention
on functional decline in very elderly patients during acute
hospitalization. JAMA Int Med. 2019;179(1):28. doi: 10.1001/
jamainternmed.2018.4869
Burtin C, Clerckx B, Robbeets C, Ferdinande P, Langer D, et al.
Early exercise in critically ill patients enhances short-term
functional recovery*. Crit Care Med. 2009;37(9):2499-505.
doi: 10.1097/CCM.0b013e3181a38937
Denehy L, Skinner EH, Edbrooke L, Haines K, Warrillow S,
et al. Exercise rehabilitation for patients with critical illness:
a randomized controlled trial with 12 months of follow-up.
Crit Care. 2013;17(4):R156. doi:10.1186/cc12835
Schujmann DS, Lunardi AC, Fu C. Progressive mobility program
and technology to increase the level of physical activity and
its benefits in respiratory, muscular system, and functionality
of ICU patients: study protocol for a randomized controlled
trial. Trials. 2018;19(1). doi: 10.1186/s13063-018-2641-4
Levine S, Nguyen T, Taylor N, Friscia ME, Budak MT, et al. Rapid
disuse atrophy of diaphragm fibers in mechanically ventilated
humans. N Engl J Med. 2008;358(13):1327-35. doi: 10.1056/
NEJMoa070447
Tipping CJ, Harrold M, Holland A, Romero L, Nisbet T, et al.
The effects of active mobilisation and rehabilitation in ICU
on mortality and function: a systematic review. Int Care Med.
;43(2):171-83. doi: 10.1007/s00134-016-4612-0
Hsieh SJ, Otusanya O, Gershengorn HB, Hope AA, Dayton
Cet al. Staged implementation of awakening and breathing,
coordination, delirium monitoring and management, and early
mobilization bundle improves patient outcomes and reduces
hospital costs. Crit Care Med. 2019;47(7):885-93. doi: 10.1097/
CCM.0000000000003765
Zhang L, Hu W, Cai Z, Liu J, Wu J, et al. Early mobilization of
critically ill patients in the intensive care unit: a systematic
review and meta-analysis. Plos ONE. 2019;14(10):e0223185.
doi: 10.1371/journal.pone.0223185
Thille AW, Boissier F, Muller M, Levrat A, Bourdin G, et al. Role
of ICU-acquired weakness on extubation outcome among
patients at high risk of reintubation. Crit Care. 2020;24(1). doi:
1186/s13054-020-2807-9
Nazwar TA, Triangto I, Pringga GA, Bal’afif F, Wardana DW.
Mobilization phases in traumatic brain injury. Acute Crit Care.
;38(3):261-70. doi: 10.4266/acc.2023.00640
Alaparthi GK, Gatty A, Samuel SR, Amaravadi SK. Effectiveness,
safety, and barriers to early mobilization in the Intensive Care
Unit. Crit Care Res Pract. 2020;2020(7840743):1-14. doi:
1155/2020/7840743
Zhang L, Hu W, Cai Z, Liu J, Wu J, et al. Early mobilization of
critically ill patients in the intensive care unit: A systematic
review and meta-analysis. Plos One. 2019;14(10):e0223185.
doi: 10.1371/journal.pone.0223185
Yang X, Zhang T, Cao L, Ye L, Song W. Early Mobilization for
critically ill patients. Resp Care. 2023;68(6):respcare.10481.
doi:10.4187/respcare.10481
Grosu HB, Lee YI, Lee J, Eden E, Eikermann M, et al. Diaphragm
muscle thinning in patients who are mechanically ventilated.
Chest. 2012;142(6):1455-60. doi: 10.1378/chest.11-1638
Moraes FS, Marengo LL, Moura MDG, Bergamaschi CC,
Sá Del Fiol F, et al. ABCDE and ABCDEF care bundles: a
systematic review of the implementation process in intensive
care units. Medicine. 2022;101(25):e29499 doi: 10.1097/
MD.0000000000029499
Schweickert WD, Pohlman MC, Pohlman AS, Nigos C,
Pawlik AJ, et al. Early physical and occupational therapy in
mechanically ventilated, critically ill patients: a randomised
controlled trial. Lancet. 2009;373(9678):1874-82. doi: 10.1016/
S0140-6736(09)60658-9
Downloads
Publicado
Edição
Seção
Licença
Copyright (c) 2025 Rodrigo César Maia Moreira, Rodrigo Marques Tonella, Lucinara Martins Silva Tallarico, Taís Mendes de Camargo, Liliane Patrícia Souza Mendes, Mariana Hoffman Barbosa, Maria Clara Xavier Salles, Marcelo Velloso

Este trabalho está licenciado sob uma licença Creative Commons Attribution-ShareAlike 4.0 International License.