Cardiovascular conditions and blood pressure as risk factors for adverse events during exercise in individuals with respiratory conditions

Authors

  • Vanessa Garcia de Lima Universidade Federal do Ceará (UFC) – Fortaleza (CE), Brazil.
  • Chayenne Chylld César Lopes Universidade Federal do Ceará (UFC) – Fortaleza (CE), Brazil.
  • Luan dos Santos Mendes Costa Universidade Federal do Ceará (UFC) – Fortaleza (CE), Brazil.
  • Andrea Felinto Moura Universidade Federal do Ceará (UFC) – Fortaleza (CE), Brazil.
  • Magno F. Formiga Universidade Federal do Ceará (UFC) – Fortaleza (CE), Brazil.
  • Rafael Mesquita Universidade Federal do Ceará (UFC) – Fortaleza (CE), Brazil.

DOI:

https://doi.org/10.1590/

Keywords:

Respiratory Tract Diseases, Exercise, Rehabilitation, Arterial Pressure, Hypotension, Orthostatic.

Abstract

This study aimed to describe cardiovascular
conditions and compare repeated measurements of systemic
blood pressure (BP) and orthostatic hypotension (HO) as risk
factors for adverse events during exercise in individuals with
chronic respiratory conditions. This was a cross-sectional
study including individuals evaluated to participate in a
rehabilitation program. Comorbidities, signs, and symptoms
of self-reported cardiovascular conditions, resting BP
(measured simultaneously in both arms with at least three
measurements), and criteria for OH were assessed. Forty-two
individuals were included: 67% were women, with a mean
age of 53±18 years, and 38% had post-COVID-19 condition.
Cardiovascular conditions were reported by up to 76%
of individuals, but only 13 required medical clearance for
exercise. A total of 85% achieved reproducible BP results
with only three measurements. The difference in systolic
BP between the full protocol and a single measurement in
one arm was −2.2 mmHg (95% CI −4.2 to −0.2). Only one
individual (3%) presented OH. Cardiovascular conditions are
common in individuals with chronic respiratory conditions
but generally do not contraindicate exercise. Furthermore,
repeated BP measurements do not appear to be necessary
in this context.

Downloads

Download data is not yet available.

References

1. World Health Organization. Chronic respiratory diseases

[Internet]. 2019 [cited 2024 Apr 16]. Available from: https://www.

who.int/health-topics/chronic-respiratory-diseases#tab=tab_1

2. World Health Organization. Coronavirus disease (COVID-19): Post

COVID-19 condition [Internet]. 2023 [cited 2026 Mar 9]. Available

from: https://www.who.int/news-room/questions-and-answers/

item/coronavirus-disease-(covid-19)-post-covid-19-condition

3. McCarthy B, Casey D, Devane D, Murphy K, Murphy E, et al.

Pulmonary rehabilitation for chronic obstructive pulmonary

disease. Cochrane Database Syst Rev. 2015;2015(4).

doi: 10.1002/14651858.CD003793.pub3

4. Osadnik CR, Gleeson C, McDonald VM, Holland AE. Pulmonary

rehabilitation versus usual care for adults with asthma. Cochrane

Database Syst Rev. 2022;2022(8). doi: 10.1002/14651858.

CD013485.pub2

5. Jimeno-Almazán A, Pallarés JG, Buendía-Romero Á, Martínez-

Cava A, Franco-López F, et al. Post-COVID-19 syndrome and

the potential benefits of exercise. Int J Environ Res Public

Health. 2021;18(10):5329. doi: 10.3390/ijerph18105329

6. Spruit MA, Singh SJ, Garvey C, ZuWallack R, Nici L, et al.

An official american thoracic society/european respiratory

society statement: key concepts and advances in pulmonary

rehabilitation. Am J Respir Crit Care Med. 2013;188(8):e13-64.

doi: 10.1164/rccm.201309-1634ST

7. Suler Y, Dinescu LI. Safety Considerations During Cardiac and

Pulmonary Rehabilitation Program. Phys Med Rehabil Clin N

Am. 2012;23(2):433-40. doi: 10.1016/j.pmr.2012.02.013

8. World Physiotherapy. World physiotherapy response to

COVID-19 briefing paper 9. safe rehabilitation approaches for

people living with long covid: physical activity and exercise.

London: World Physiotherapy; 2021.

9. Barroso WKS, Rodrigues CIS, Bortolotto LA, Mota-Gomes

MA, Brandão AA, et al. Diretrizes Brasileiras de hipertensão

arterial – 2020 [Internet]. Arq Bras Cardiol. 2021 [cited 2026

Mar 9];116(3):516-658. Available from: https://abccardiol.org/

article/diretrizes-brasileiras-de-hipertensao-arterial-2020/

10. Malachias M, Souza W, Plavnik F, Rodrigues C, Brandão A, et

al. 7th Brazilian Guideline of Arterial Hypertension. Arq Bras

Cardiol. 2016;107(3):1-6. doi: 10.5935/abc.20160151

11. von Elm E, Altman DG, Egger M, Pocock SJ, Gøtzsche PC, et

al. The strengthening the reporting of observational studies in

epidemiology (STROBE) statement: guidelines for reporting

observational studies. J Clin Epidemiol. 2008;61(4):344-9.

doi: 10.1016/j.jclinepi.2007.11.008

12. Pereira CAC, Sato T, Rodrigues SC. New reference values for

forced spirometry in white adults in Brazil. J Bras Pneumol.

2007;33(4):397-406. doi: 10.1590/S1806-37132007000400008

13. Albuquerque VS, Dal Corso S, Amaral DP, Oliveira TMD, Souza

GF, et al. Normative values and reference equation for the

six-minute step test to evaluate functional exercise capacity:

a multicenter study. J Bras Pneumol. 2022;48(4):e20210511.

doi: 10.36416/1806-3756/e20210511

14. Camelier A, Rosa FW, Salmi C, Nascimento OA, Cardoso F,

et al. Using the Saint George’s Respiratory Questionnaire to

evaluate quality of life in patients with chronic obstructive

pulmonary disease: validating a new version for use in

Brazil. J Bras Pneumol. 2006;32(2):114-22. doi: 10.1590/

S1806-37132006000200006

15. Kovelis D, Segretti NO, Probst VS, Lareau SC, Brunetto AF, et

al. Validation of the Modified Pulmonary Functional Status and

Dyspnea Questionnaire and the Medical Research Council scale

for use in Brazilian patients with chronic obstructive pulmonary

disease. J Bras Pneumol. 2008;34(12):1008-18. doi: 10.1590/

S1806-37132008001200005

16. Charlson M, Szatrowski TP, Peterson J, Gold J. Validation of a

combined comorbidity index. J Clin Epidemiol. 1994;47(11):1245-

51. doi: 10.1016/0895-4356(94)90129-5

17. Ghorayeb N, Stein R, Daher DJ, Silveira AD, Ritt LEF, et al. The

Brazilian Society of Cardiology and Brazilian Society of Exercise

and Sports Medicine Updated Guidelines for Sports and

Exercise Cardiology – 2019. Arq Bras Cardiol. 2019;112(3):326-

68. doi: 10.5935/abc.20190048

18. American College of Sports Medicine. ACSM’s guidelines for

exercise testing and prescription. 11th ed. Philadelphia: Lippincott

Williams & Wilkins; 2021.

19. Global Initiative for Chronic Obstructive Lung Disease. Global

Strategy for the Diagnosis, Management, and Prevention

of Chronic Obstructive Pulmonary Disease – 2024 report

[Internet]. 2023 [cited 2026 Mar 9]. Available from: https://

www.goldcopd.org/

20. Mesquita R, Franssen FME, Houben-Wilke S, Uszko-Lencer

NHMK, Vanflerteren LEGW, et al. What is the impact of impaired

left ventricular ejection fraction in COPD after adjusting for

confounders? Int J Cardiol. 2016;225:365-70. doi: 10.1016/j.

ijcard.2016.10.016

21. Global Initiative for Asthma. Global Strategy for Asthma

Management and Prevention [Internet]. 2023 [updated 2023;

cited 2026 Mar 9]. Available from: http://www.ginasthma.org/

22. Ministério da Saúde (BR). Técnica de aferição da Pressão Arterial

(PA) [Internet]. Brasil: Ministério da Saúde ; [cited 2026 Mar 9].

Available from: https://linhasdecuidado.saude.gov.br/

portal/hipertensao-arterial-sistemica-(HAS)-no-adulto/

tecnica-afericao-pa

23. Mesquita R, Donária L, Genz IC, Pitta F, Probst VS. Respiratory

muscle strength during and after hospitalization for COPD

Exacerbation. Respir Care. 2013;58(12):2142-9. doi: 10.4187/

respcare.02393

Downloads

Published

2026-07-20

Issue

Section

Original Research

How to Cite

Cardiovascular conditions and blood pressure as risk factors for adverse events during exercise in individuals with respiratory conditions. (2026). Fisioterapia E Pesquisa, 33(n cont), e24010626. https://doi.org/10.1590/