Osteoradionecrosis of the jaws: case series treated with adjuvant low-level laser therapy and antimicrobial photodynamic therapy
DOI:
https://doi.org/10.1590/1678-7757-2017-0172Keywords:
Osteoradionecrosis, Oral cancer, Radiotherapy, Low-level laser therapy, Antimicrobial photodynamic therapyAbstract
Background: Osteoradionecrosis of the jaw (ORNJ) is the most severe and complex sequel of head and neck radiotherapy (RT) because of the bone involved, it may cause pain, paresthesia, foul odor, fistulae with suppuration, need for extra oral communication and pathological fracture. We treated twenty lesions of ORNJ using low-level laser therapy (LLLT) and antimicrobial photodynamic therapy (aPDT). The objective of this study was to stimulate the affected area to homeostasis and to promote the healing of the oral mucosa. Methods: We performed aPDT on the exposed bone, while LLLT was performed around the bone exposure (red spectrum) and on the affected jaw (infrared spectrum). Monitoring and clinical intervention occurred weekly or biweekly for 2 years. Results: 100% of the sample presented clinical improvement, and 80% presented complete covering of the bone exposure by intact oral mucosa. Conclusion:
LLLT and aPDT showed positive results as an adjuvant therapy to treat ORNJ.
Downloads
Downloads
Published
Versions
- 2022-08-31 (2)
- 2022-08-31 (1)
Issue
Section
License
Copyright (c) 2022 Journal of Applied Oral Science

This work is licensed under a Creative Commons Attribution 4.0 International License.
Todo o conteúdo do periódico, exceto onde está identificado, está licenciado sob uma Licença Creative Commons do tipo atribuição CC-BY.