Analysis of the tissue answer regarding two root canal sealers

Authors

  • Maria Renata Giazzi Nassri Universidade de Mogi das Cruzes
  • Raphael Carlos Comelli Lia Universidade de Ribeirão Preto
  • Antonio Carlos Bombana Universidade de São Paulo; FO

DOI:

https://doi.org/10.1590/S1678-77572003000100003

Keywords:

Root canal filling materials, Biocompatible materials

Abstract

On the present study, two root canal sealers have been comparatively analysed, Sealapex® and Apexit®, in relation to its biological compatibility to subcutaneous tissue. For this analysis, twelve male rats weighing in average 250 g have been used, divided in three groups, according with its experimental time, 7, 21 and 45 days. Making part of the study, four incisions on the dorsal area of each rat have been made, where were implanted four polyetilene tubes, filled with the testing root canal sealers. After seven, twenty-one and forty-five days of the surgery, the animals have been sacrified and the tissues have been laboratory processed to obtain the histological cut coloured by hematoxilin-eosin, and subsequent quality analysis of the results. From this results, were verified that both sealers caused tissue's intense macrofagic activity, in the experimental time. Apexit caused a more agressive tissue reaction, in relation to the Sealapex, with also higher macrofagic activity. Sealapex showed better results in comparison to inflamatory intensitivity and tissue repair level.

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Published

2003-03-01

Issue

Section

Original Articles

How to Cite

Analysis of the tissue answer regarding two root canal sealers . (2003). Journal of Applied Oral Science, 11(1), 9-14. https://doi.org/10.1590/S1678-77572003000100003