Immunohistochemical expression of vimentin and HHF-35 in giant cell fibroma, fibrous hyperplasia and fibroma of the oral mucosa

Authors

  • Márcia Cristina da Costa Miguel UFRN; Programa de Pós-Graduação em Patologia Oral
  • Emanuel Savio de Souza Andrade FOP-UPET; Patologia Bucal
  • Danielle Albuquerque Pires Rocha FOP-UPET; Patologia Bucal
  • Roseana de Almeida Freitas UFRN; Professora Doutora da Disciplina de Patologia Oral
  • Lélia Batista de Souza UFRN; Professora Doutora da Disciplina de Patologia Oral

DOI:

https://doi.org/10.1590/S1678-77572003000100013

Keywords:

Giant cell fibroma, Fibrous hyperplasia, Fibroma, Oral mucosa, Immunohistochemistry

Abstract

The giant cell fibroma, fibrous hyperplasia and fibroma are the most frequent fibrous oral lesions, sharing clinical and histopathological features. The purpose of this study was to investigate the immunoreactivity of the large stellate-shaped mononuclear and multinucleated cells, reported as the most characteristic histological feature of the giant cell fibroma but present occasionally in fibrous hyperplasia and fibroma, for the antibodies vimentin and HHF-35 in order to detect phenotypical characteristic of these cells. The results showed in the most of cases positive staining for vimentin, suggesting a fibroblast phenotype for these cells.

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Published

2003-03-01

Issue

Vol. 11 No. 1 (2003)

Section

Original Articles

License

Todo o conteúdo do periódico, exceto onde está identificado, está licenciado sob uma Licença Creative Commons do tipo atribuição CC-BY.

 

 

How to Cite

Immunohistochemical expression of vimentin and HHF-35 in giant cell fibroma, fibrous hyperplasia and fibroma of the oral mucosa . (2003). Journal of Applied Oral Science, 11(1), 77-82. https://doi.org/10.1590/S1678-77572003000100013