Pool of bovine morphogenetic proteins and guided tissue regeneration in the treatment of intrabony periodontal defects: I- Clinical measurements

Authors

  • Maria do Carmo Machado Guimarães University of Sao Paulo; Bauru Dental School; Department of Prosthodontics and Periodontics
  • Euloir Passanezi University of Sao Paulo; Bauru Dental School; Department of Prosthodontics and Periodontics
  • Adriana Campos Passanezi Sant'Ana University of Sao Paulo; Bauru Dental School; Department of Prosthodontics and Periodontics
  • Sebastião Luiz Aguiar Greghi University of Sao Paulo; Bauru Dental School; Department of Prosthodontics and Periodontics

DOI:

https://doi.org/10.1590/S1678-77572004000100013

Keywords:

Periodontal regeneration, Intrabony defects, Bone morphogenetic proteins

Abstract

The purpose of this study was to evaluate the effect of the pool of bovine BMPs on the treatment of intrabony defects. The sample comprised 15 patients aged 26 to 57 years old presenting with 10 pairs of lesions of 2 or 3 walls or 2-3 walls ³5mm, located in the same type teeth (premolar or molar) and same jaw. The test defects were treated with combination of a pool of bovine bone morphogenetic and resorbable hydroxyapatite carrier (BMPs- HA), bovine demineralized bone matrix (MB) and coverage by a bovine collagen barrier membrane. The control defects were treated with MB-HA and covered by a bovine collagen membrane. The clinical measurements at six months after therapy in the test group revealed a reduction in the mean probing pocket depth (PPD) of 1.63 ± 1.41mm (B) and 1.93 ± 0.96mm (L) and a mean change in the clinical attachment level (CAL) of 1.60 ± 1.16mm (B) and 1.46 ± 0.97mm (L). The control group showed a mean reduction of PPD of 1.93 ± 1.34mm (B) and 2.0 ± 1.51mm (L) and a mean change of CAL of 1.03 ± 1.24mm (B) and 1.30 ± 1.14 mm (L). The analysis of variance (ANOVA) demonstrated that the changes in the clinical parameters were statistically significant (p<0.05). There were no significant differences between the test and controls subjects (Student's test, p<0.005). These findings suggest that the use of a pool of bovine BMPs do not provide added effects to GTR in the treatment of intrabony defects.

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Published

2004-03-01

Issue

Section

Original Articles

How to Cite

Pool of bovine morphogenetic proteins and guided tissue regeneration in the treatment of intrabony periodontal defects: I- Clinical measurements . (2004). Journal of Applied Oral Science, 12(1), 70-77. https://doi.org/10.1590/S1678-77572004000100013