Biocompatibility of acellular dermal matrix graft evaluated in culture of murine macrophages

Authors

  • Ana Paula Vendramini UNESP; Araraquara Pharmaceutical Science School
  • Rafaela Fernanda Melo UNESP; Araraquara Dental School
  • Rosemary Adriana Chiérici Marcantonio UNESP; Araraquara Dental School
  • Iracilda Zepone Carlos UNESP; Araraquara Pharmaceutical Science School

DOI:

https://doi.org/10.1590/S1678-77572006000200001

Keywords:

Dermal allograft, Macrophages, Nitric oxide, Hydrogen peroxide

Abstract

The acellular dermal matrix allograft has been used as an alternative to autogenous palatal mucosal graft. The aim of this study was the evaluation of the biocompatibility of an acellular dermal matrix (AlloDerm®) in culture of macrophages. For hydrogen peroxidase determination we used the method of Pick & Kesari, and the Griess method for nitric oxide determination,. Statistical analysis showed no significant difference (p < 0,05) in the release of nitric oxide and hydrogen peroxide by the macrophages exposed to acellular dermal matrix and the negative control. The results suggest that acellular dermal matrix did not activate the cell inflammatory response.

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Published

2006-04-01

Issue

Vol. 14 No. 2 (2006)

Section

nd

License

Todo o conteúdo do periódico, exceto onde está identificado, está licenciado sob uma Licença Creative Commons do tipo atribuição CC-BY.

 

 

How to Cite

Vendramini, A. P., Melo, R. F., Marcantonio, R. A. C., & Carlos, I. Z. (2006). Biocompatibility of acellular dermal matrix graft evaluated in culture of murine macrophages . Journal of Applied Oral Science, 14(2), 67-70. https://doi.org/10.1590/S1678-77572006000200001