Rate of orotracheal extubation failure in a sample of cancer patients

Authors

DOI:

https://doi.org/10.11606/issn.1679-9836.v99i6p545-555

Keywords:

Physiotherapy, Extubation, Intensive care, Oncology, Intensive care units, Weaning, Intubation

Abstract

Objective: To classify the rate of orotracheal extubation failure (EF) in a sample of cancer patients and to evaluate the association between FE, mortality index and clinical events. Methods: A retrospective descriptive study was carried out to collect data from the medical records from March 2012 to May 2017 involving 1,088 medical records that required invasive ventilatory support during ICU admission. Results: 39 patients required early reintubation during ICU stay, in which the EF incidence rate was 3.6%, mean age 59.6 years, with a predominance of males, with a high incidence of respiratory complications and pneumonia. The mean reintubation time after extubation was 16.5 ± 14.0 h, with respiratory fatigue (48.7%) being the main reason for reintubation, and the main outcome was death (56.4%). Three univariate and multivariate regression models were used for the reintubation time, days of ICU stay (R2: 61.7%) and death (R2: 78.8), which demonstrated independent variables capable of predicting change in the models studied. The model that best responded to our goal was death with explained variance of 78.8%. Conclusion: Our findings demonstrated a low incidence of extubation failure and the importance of identifying specific risk factors for the cancer population, predicting that such factors could influence the need for reintubation.

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Author Biographies

  • Camilla Giovana Agu, AC Camargo Câncer Center. Departamento de Fisioterapia

    Instituição onde foi realizado o trabalho: AC Camargo Cancer Center, Departamento de Fisioterapia.
    Apresentado no European Respiratory Society International Congress, Paris, França, 15-19 set. 2018.

    Fisioterapeuta com residencia Multiprofissional em Fisioterapia em Oncologia pelo AC camargo Cancer Center, 2018. Departamento de Fisioterapia do AC Camargo Câncer Center (AC Camargo). São Paulo, SP, Brasil. 

  • Pedro Caruso, Universidade de São Paulo. Faculdade de Medicina. Hospital das Clínicas. Instituto do Coração, Divisão Pulmonar.

    Graduação em Medicina pela Universidade de São Paulo (1990) e doutorado em Pneumologia pela Universidade de São Paulo (2000). Atualmente é médico assistente e professor colaborador médico da Disciplina de Pneumologia da Universidade de São Paulo. Coordenador médico da UTI do Hospital A.C. Camargo. Tem experiência na área de UTI e Pneumologia, atuando principalmente nos seguintes temas: desmame da ventilação mecânica, músculos respiratórios e pesquisa sobre pacientes com câncer admitidos em UTI. 

  • Indiara Soares Oliveira, AC Camargo Câncer Center. Departamento de Fisioterapia

    Graraduação em Fisioterapia pela Faculdade de Saúde, Ciências Humanas e Tecnológicas do Piauí (2010), Pós graduação em Fisioterapia Oncológica e Hospitalar (2011) pela Fundação Antônio Prudente - Hospital A. C. Camargo Cancer Center, Mestrado em Fisioterapia pela Universidade Cidade de São Paulo - UNICID (2013) e Doutorado em Fisioterapia pela Universidade Cidade de São Paulo - UNICID (2017). Atualmente é fisioterapeuta do Hospital AC Camargo Cancer Center, supervisora do programa de residência em fisioterapia do Hospital AC Camargo Cancer Center e professora do curso de medicina da Universidade Nove de Julho (UNINOVE) . Suas preferências de pesquisa são: estudos relacionados a área de oncologia, prognóstico, metodologia.

  • Celena Freire Friedrich, AC Camargo Câncer Cente. Departamento de Fisioterapia

    Fisioterapeuta, diretora do Departamento de Fisioterapia do AC Camargo Câncer Center (AC Camargo) – São Paulo (Brasil)

  • Ivan Peres Costa, Universidade Nove de Julho

    Docente dos cursos de Fisioterapia e Medicina Guarulhos da Universidade Nove de Julho (UNINOVE) - São Paulo, SP. BR. 

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Published

2020-12-20

Issue

Vol. 99 No. 6 (2020)

Section

Artigos/Articles

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Copyright (c) 2020 Camilla Giovana Agu, Pedro Caruso, Indiara Soares Oliveira, Celena Freire Friedrich, Ivan Peres Costa

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This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

How to Cite

Agu, C. G., Caruso, P., Oliveira, I. S., Friedrich, C. F., & Costa, I. P. (2020). Rate of orotracheal extubation failure in a sample of cancer patients. Revista De Medicina, 99(6), 545-555. https://doi.org/10.11606/issn.1679-9836.v99i6p545-555