Comparative evaluation between Mindray BC-6800 and URIT 5500 hematology analyzers, with emphasis on the ability to detect blasts in patients with acute leukemia
DOI:
https://doi.org/10.11606/issn.1679-9836.v101i2e-172549Keywords:
Blood cell count, Clinical alarms, Granulocyte precursor cells, Lymphoid progenitor cellsAbstract
Compare the ability of the BC-6800 (Mindray) and URIT 5500 hematological analyzers to signal the presence of blasts in patients with acute leukemia. Thirteen samples of peripheral blood containing myeloid or lymphoid blasts, from a cancer hospital in Belém - Pará, previously immunophenotyped by flow cytometry were analyzed to determine the capacity of the Mindray BC-6800 and URIT 5500 equipment in signaling the presence of these cells in the leukocyte scatter or by emitting flags. To assess the existence of statistical difference between the results of red blood cells, hemoglobin, leukocytes and platelets obtained by the BC 6800 (Mindray) and URIT 5500 equipments, the non-parametric ANOVA test was applied for analysis of variance of the samples, which showed that there was no statistical difference between these analytes. Statistical method was not applied for leukocyte differential counts, as the URIT 5500 equipment did not generate numerical data for the pathological samples. Both devices were able to generate flags and spatial changes from the leukocyte scatter to pathological samples, however, the BC 6800 (Mindray) analyzer was the only one to change the color of the blast population in the leukocyte scatter. BC-6800 (Mindray) and URIT 5500 analyzers showed good ability to signal, through flags and leukocyte scatter, for the presence of myeloid or lymphoid blasts in pathological samples.
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