Coagulação intravascular disseminada: uma abordagem diagnóstica
DOI:
https://doi.org/10.11606/issn.1679-9836.v100i4p366-374Palavras-chave:
Coagulação intravascular disseminada, Diagnóstico, Diagnóstico diferencial.Resumo
A coagulação intravascular disseminada é caracterizada pela desregulação na homeostase da coagulação e é desencadeada por várias afecções. Essa síndrome possui alta taxa de mortalidade -45 a 78%- sendo preponderante a sua identificação. Entretanto, o seu reconhecimento é desafiador por existir várias etiologias subjacentes, diagnósticos diferenciais, dificuldade na interpretação de exames e rápida evolução na forma aguda. Assim, foi realizada uma revisão narrativa utilizando PUBMED e SciELO, a fim de estruturar informações para melhor compreensão e acurácia no diagnóstico da coagulação intravascular disseminada.
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Levi M, Scully M. How I treat disseminated intravascular coagulation. Blood. 2018;131(8):845-54. doi: 10.1182/blood-2017-10-804096.
Boral BM, Williams DJ, Boral LI. Disseminated Intravascular Coagulation. Am J Clin Pathol. 2016;146:670-80. doi: 10.1093/AJCP/AQW195.
Levi M. Pathogenesis and diagnosis of disseminated intravascular coagulation. Int J Lab Hematol. 2018;40(1):15–20. doi: 10.1111/ijlh.12830.
Toh CH, Alhamdi Y, Abrams ST. Current pathological and laboratory considerations in the diagnosis of disseminated intravascular coagulation. Ann Lab Med. 2016;36(6):505–12. doi: 10.3343/alm.2016.36.6.505.
Wada H, Thachil J, Di Nisio M, Mathew P, Kurosawa S, Gando S, et al. Guidance for diagnosis and treatment of DIC from harmonization of the recommendations from three guidelines. J Thromb Haemost. 2013;11:761–7. doi: 10.1111/jth.12155.
Levi M. Disseminated intravascular coagulation: What's new? Crit Care Clin. 2005;21(3):449-67. doi: 10.1016/j.ccc.2005.02.001.
Wada H, Matsumoto T, Yamashita Y. Diagnosis and treatment of disseminated intravascular coagulation (DIC) according to four DIC guidelines. J Intensive Care. 2014;2(1):15. doi: 10.1186/2052-0492-2-15.
Papageorgiou C, Jourdi G, Adjambri E, Walborn A, Patel P, Fareed J, et al. Disseminated intravascular coagulation: an update on pathogenesis, diagnosis, and therapeutic strategies. Clin Appl Thromb Hemost. 2018;24(9):8–28. doi: 10.1177/1076029618806424.
Touaoussa A, Youssi HE, Hassani IE, Hanouf D, Bergui IE, Zoulati G, et al. Disseminated intravascular coagulation: clinical and biological diagnosis. Ann Biol Clin. 2015;73(6):657-63. doi: 10.1684/abc.2015.1100.
Papageorgiou C, Jourdi G, Adjambri E, Walborn A, Patel P, Fareed J, et al. Disseminated Intravascular Coagulation: An Update on Pathogenesis, Diagnosis, and Therapeutic Strategies. Clin Appl Thromb Hemost. 2018;24(9):8S-28S. doi: 10.1177/1076029618806424.
Levi M, Van der Poll T. Disseminated intravascular coagulation: a review for the internist. Intern Emerg Med. 2013; 8(1):23-32. doi: 10.1007/s11739-012-0859-9.
Levi M, Jonge E, Van der Poll T, Cate HT. Advances in the understanding of the pathogenetic pathways of disseminated intravascular coagulation result in more insight in the clinical picture and better management strategies. Semin Thromb Hemost. 2001;27(6):569-75. doi: 10.1055/s-2001-18862.
Fruchtman S , Aledort LM. Disseminated intravascular coagulation. J Am Coll Cardiol. 1986;8(6):159-67. doi: 10.1016/s0735-1097(86)80017-1.
Kahhale S, Francisco RPV, Zugaib M. Pré-eclampsia. Rev Med. (São Paulo). 2018;97(2):226-34. doi: http://dx.doi.org/10.11606/issn.1679-9836.v97i2p226-234
Haram K, Mortensen JH, Mastrolia SA, Erez O. Disseminated intravascular coagulation in the HELLP syndrome: how much do we really know? J Matern Fetal Neonatal Med. 2017;30(7):779-88. doi: 10.1080/14767058.2016.1189897.
Thachil J, Toh CH. Disseminated intravascular coagulation in obstetric disorders and its acute haematological management. Blood Rev. 2009;23(4):167-76. doi: 10.1016/j.blre.2009.04.002
Souza R, Grochowski RA, Junior CAM, Groppi B, Rezende CAL. Diagnosis and management of Hellp Syndrome. Rev Med Minas Gerais. 2009;19(4):30-3 Disponível em: http://rmmg.org/artigo/detalhes/1097
Wada H, Matsumoto T, Suzuki K, Imai H, Katayama N, Iba T, et al. Differences and similarities between disseminated intravascular coagulation and thrombotic microangiopathy. Thromb J. 2018;16:14. doi: 10.1186/s12959-018-0168-2.
Polito MG, Kirsztajn GM. Microangiopatias trombóticas: púrpura trombocitopênica trombótica e síndrome hemolítico-urêmica Thrombotic microangiopathies: thrombotic thrombocytopenic purpura / hemolytic uremic syndrome. J Bras Nefrol. 2010;32(3):303-15. doi: https://doi.org/10.1590/S0101-28002010000300013
Arnold DM, Patriquin CJ, Nazy I. Thrombotic microangiopathies: a general approach to diagnosis and management. CMAJ. 2017;189(4):E153-E159. doi: https://doi.org/10.1503/cmaj.160142
Iba T, Levy JH, Wada H, Thachil J, Warkentin TE, Levi M. Differential diagnosis for sepsis‐induced disseminated intravascular coagulation: communication from the SSC of the ISTH. J Thromb Haemost. 2019;17(2):415-9. doi: 10.1111/jth.14354
Karpatkin M. Diagnosis and Management of Disseminated Intravascular Coagulation. Pediatr Clin North Am. 1971;18(1):23-38. doi: 10.1016/S0031-3955(16)32520-2.
Toh CH, Dennis M. Current clinical practice DIC 2002: a review of disseminated intravascular coagulation. Hematology. 2013;8:2:65-71. doi: https://doi.org/10.1080/1024533031000084213
WanP, Tong HS, Zhang XQ, Duan PK, Tang YQ, Su L. Diagnosis of overt disseminated intravascular coagulation in critically Ill adults by Sonoclot coagulation analysis. Int J Hematol. 2014;100(2):125-31. doi: 10.1007/s12185-014-1601-3.
Gando S, Levi M, Toh CH. Disseminated intravascular coagulation. Nat Rev Dis Primers. 2016;2:16037. doi: 10.1038/nrdp.2016.37.
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Copyright (c) 2021 Alice Maia Marinho de Andrade, Ramona Dias Horta , Mariana Soares Vieira , Mayra Aline Chaves
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