Herpes vírus simples e carcinoma cérvico-uterino

Abstract

An important role has been ascribed to the herpes-vírus simplex (HSV) in the etiology of uterine cervical cancer. We have studied 60 women, 30 of them with cervical uterine cancer and another 30 without them. We performed clinicai, cytological, cytophatic and sorological studies. The last one permited to conclude past infections and the others the presence of the virus concomitantly. The clinical study found out the antecedents of the women and their partners concerned signs and symptoms of the disease. In addition we performed a careful gynecological exam in order to detect the viral disease. By the other hand we searched cytological alterations characteristical of the presence of the virus in cervical smears. The cytopathic effects was observed in rabbit cornea culture cells (SIRC-cells). The sorological study consisted in a complement fixation microtechnics againt antigen of the herpes virus (50% of hemolysis). We compared statistically the results of the two groups and did not find any significative difference relatively of the various parameters studied.