Platelet activation in different clinical forms of the coronary artery disease: roll of -Selectin and others platelet markers in the stable and unstable angina
DOI:
https://doi.org/10.11606/issn.1679-9836.v85i1p16-21Keywords:
latelet activation, Coronary disease/pathology, P-Selectin/analysis, Biological markes/analysis, Angina, unstable.Abstract
PURPOSE: Markers of platelet activation are elevated in coronary artery disease.We sought to identify the presence and the potential associations of different markers of platelet activation. METHODS: We studied patients with unstable angina (n = 28), patients with stable angina (n = 36) and patients without coronary artery disease (n = 30); sex and age matched. Blood levels of the adhesion molecule P-selectin, Thromboxane B2 and Serotonin were measured by enzyme immunoassays. RESULTS: When we compared the groups the results were: sP-selectin, thromboxane B2 and serotonin levels were significantly higher in patients with unstable angina than in patients with stable angina. CONCLUSION: These markers of platelet activation were able to identify unstable forms of coronary artery disease.Downloads
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Published
2006-03-16
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Medical Articles
How to Cite
Soeiro, A. de M., Araujo, L. F., Venturinelli, M. L., & Serrano Júnior, C. V. (2006). Platelet activation in different clinical forms of the coronary artery disease: roll of -Selectin and others platelet markers in the stable and unstable angina. Revista De Medicina, 85(1), 16-21. https://doi.org/10.11606/issn.1679-9836.v85i1p16-21