The relevance of reticulocytosis in the classification of hereditary spherocytosis

case report

Abstract

The Hereditary spherocytosis is a haemolytic disease of genetic origin polissômica and may be autosomal dominant or recessive. Its clinical status is represented by anemia, reticulocytosis, indirect hyperbilirubinemia and the presence of numerous spherocytes in the bloodstream, which are altered in the osmotic fragility test, revealing a lower resistance to lysis. The laboratory tests are of great importance in the taking of conducts, nevertheless, they must be interpreted together with the clinical history, since this still shows itself to be sovereign. Although reticulocytosis is a criterion for classifying patients with spherocytosis as severe, it should be carefully evaluated along with other clinical and laboratory parameters. It is of great importance the holistic look of the doctor on the patient, as well as the critical analysis of the use of clinical protocols.