Acute maxillary osteomyelitis in a patient affected by malignant infantile osteopetrosis: report of a rare case of survival
DOI:
https://doi.org/10.11606/issn.1679-9836.v99i4p405-410Keywords:
Osteopetrosis, Complications, Survival, OsteomyelitisAbstract
Infantile malignant osteopetrosis (IMO) is the most severe form of osteopetrosis (OP), which is a group of rare and hereditary disorders that affect the human skeleton by increasing bone density. One of its main consequences is bone marrow invasion by bone sclerosis, leading to progressive bone marrow failure and aplasia, which predisposes to several infections, including osteomyelitis. It is a disease with 99% mortality by the age of ten and an incidence of 1:500,000 live births. The only available treatment is early bone marrow transplantation. The case report describes a 14-year old male patient, diagnosed with IMO since childhood and admitted to the emergency room of the Albert Sabin Children’s Hospital with right facial edema and local pain that started one month before admission. Acute osteomyelitis of the maxilla was diagnosed based on physical examination and complementary tests. In addition to the current condition, the patient had several complications from his underlying disease. He developed sepsis during hospitalization, used antibiotic therapy, and was discharged after one month for home palliative care.
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