Quality of stress ulcer prophylaxis in a universitary hospital in Brazil

Authors

DOI:

https://doi.org/10.11606/issn.1679-9836.v99i2p122-127

Keywords:

Disease prevention, Gastric ulcer, Gastric ulcer/prevention & control, Prescriptions, Proton pump inhibitors, Histamine H2 antagonists, Hospitalization, Prophylaxis

Abstract

Aims: Though recommended for patients with high risk for upper gastrointestinal bleeding, stress ulcer prophylaxis is not always correctly prescribed in most hospitals. The objective of this study is to evaluate the adequation of stress ulcer prophylaxis in a universitary hospital. Methods: A cross-sectional analysis of the medical prescriptions of patients hospitalized in clinical, surgical and critical units of a universitary hospital was performed during 30 days. Prescriptions of patients using gastric protectors for a non-prophylactic purpose were excluded. The criteria for stress ulcer prophylaxis evaluation was based on recommendations from UpToDate® online database. Results: 358 prescriptions were analyzed, of which 17 were excluded. Of the 341 prescriptions included for stress ulcer analysis, 205 (60.1%) prescriptions were incorrect. Overprescription was the main reason of inadequacy, found in 175 cases (85.4%). The inadequacies in the prescriptions of the surgical units (80%) were higher when compared to the clinical (54.1%) and critical units (52.5%) (p < 0.001). Conclusions: important rates of incorrect stress ulcer prophylaxis prescriptions were found, mainly due to overprescription. Higher rates of inadequacies were found in surgical units. This scenario highlights the lack of scientific guidelines, efficient local protocols and professionals’ knowledge or acceptance regarding stress ulcer prophylaxis.

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Author Biographies

  • Guilherme da Silva Fioramonte, Federal University of Paraná

    Acadêmico de Medicina da Universidade Federal do Paraná.

  • Giovanna Daneluz de Brito, Federal University of Paraná

    Acadêmica de Medicina da Universidade Federal do Paraná.

  • Gustavo Lenci Marques, Universidade Federal do Paraná, Departamento de Clínica Médica

    Professor adjunto do Departamento de Clínica Médica da Universidade Federal do Paraná e médico cardiologista do Hospital de Clínicas da Universidade Federal do Paraná. Coordenador Adjunto do Curso de Medicina da Pontifícia Universidade Católica do Paraná, Curitiba, Paraná, Brasil.

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Published

2020-04-23

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Section

Artigos/Articles

How to Cite

Fioramonte, G. da S., Brito, G. D. de, & Marques, G. L. (2020). Quality of stress ulcer prophylaxis in a universitary hospital in Brazil. Revista De Medicina, 99(2), 122-127. https://doi.org/10.11606/issn.1679-9836.v99i2p122-127