Unusual case report of acute evolution hairy cell leukemia in a young adult patient, Amazônia, Brazil
DOI:
https://doi.org/10.11606/issn.1679-9836.v100i2p189-192Keywords:
Hairy cell leukemia, Fatal outcome, Leukocytosis, Flow cytometryAbstract
Hairy cell leukemia (HCL) is a rare disease of unknown origin and indolent course, which is detected in a complete blood count associated by pancytopenia and lymphocytes with cytoplasmic projections. This study presents a case report of a 31-year-old male patient, with pallor and no splenomegaly, who was admitted to the Municipal Hospital of Rondon do Pará, Amazônia, on December 31, 2018 to perform laboratory tests due to the worsening of his general condition. The complete blood count revealed: anemia (hemoglobin level of 7.5 g/dL and hematocrit level of 20%), thrombocytopenia (28,200/mm3) and hyperleukocytosis (179,000/mm3) while 88% of lymphocytes presented thin and elongated cytoplasmic projections suggestive of hairy cells. On January 7, 2019, the patient’s condition worsened, resulting in death before the diagnostic confirmation of the immunophenotyping test, which revealed a clonal population of 68.3% of hairy cells that expressed antigens CD19, CD20, CD79b, CD23, IgM, CD200, CD38, FMC-7, CD25 and CD103. It was not possible to determine which factors were decisive to this situation.
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