Prevalence of sarcopenia in patients with Alzheimer’s disease

Authors

DOI:

https://doi.org/10.11606/issn.1679-9836.v101i4e-176416

Keywords:

Epidemiology, Alzheimer’s disease, Prevalence, Sarcopenia

Abstract

Objective: To demonstrate the association between Alzheimer’s disease (AD) and the development of sarcopenia in patients who were diagnosed with AD in 2018 at the Polyclinic of Londrina. Method: Retrospective cohort study with n of 36 patients, who were interviewed in person in 2019, where they had performed the Mini-Mental State Examination (MMSE), Basic Activities of Daily Living (ABVD), SARC-F, BMI, calf circumference measure (CC) and, for those suspected of sarcopenia, the hand grip strength measurement test and the Sit and Stand Test were applied. The obtained results were compared to the outcome of the 2018 tests (year of AD diagnosis). Results: Patients diagnosed with Alzheimer’s Disease in 2018 showed an increase in dependence for performing BADL (p = 0.049) and a decrease in MMSE (p = 0.011), BMI (p = 0.027) and CC, in 2019 assessments. Conclusion: The prevalence of sarcopenia in patients with AD was 34% after one year of disease progression, causing a reduction in quality of life and an increase in the need for a caregiver for simple daily tasks.

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Author Biographies

  • Paola Christina Antoniassi, Pontifical Catholic University of Paraná

    Acadêmica do 6º ano do curso de Medicina da Pontifícia Universidade Católica do Paraná – Campus Londrina.

  • Nicole Sophia Froehner , Pontifical Catholic University of Paraná

    Acadêmica do 6º ano do curso de Medicina da Pontifícia Universidade Católica do Paraná – Campus Londrina.

  • Milena Laís Maçan, Pontifical Catholic University of Paraná

    Acadêmica do 6º ano do curso de Medicina da Pontifícia Universidade Católica do Paraná – Campus Londrina.

  • Lindsey Mitie Nakakogue , Pontifical Catholic University of Paraná

    Médica Geriatra e mestre, docente da Pontifícia Universidade Católica do Paraná – Campus Londrina.

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Published

2022-07-15

Issue

Section

Artigos Originais/Originals Articles

How to Cite

Antoniassi, P. C., Froehner , N. S. ., Maçan, M. L., & Nakakogue , L. M. (2022). Prevalence of sarcopenia in patients with Alzheimer’s disease. Revista De Medicina, 101(4), e-176416. https://doi.org/10.11606/issn.1679-9836.v101i4e-176416