Metabolic syndrome and the gravity of COVID-19: an integrative review
DOI:
https://doi.org/10.11606/issn.1679-9836.v102i6e-192370Keywords:
Covid 19;, Metabolic syndrome adultsAbstract
COVID-19 disease caused by the SARS-CoV-2 coronavirus (Coronavirus-2 severe acute respiratory syndrome) represents a global public health challenge. Evidence presented looking that feature components of metabolic syndrome tend to have a worse prognosis. Metabolic syndrome is defined as a set of metabolic disorders that include insulin resistance, dyslipidemia, central obesity and hypertension, which are risk factors for the development of several chronic diseases, including type 2 diabetes and cardiovascular diseases. The aim of the present study was to integratively review the literature on the impact of metabolic syndrome and its components on the outcome of patients with COVID-19. This study is an integrative literature review. Articles from 2020 and 2021 were selected in Pubmed and the Virtual Health Library using the descriptors: “COVID-19”, “metabolic syndrome”, “adults”. The inclusion criteria adopted were: primary articles performed with adults; available in full; in Portuguese, English and Spanish. Initially 372 studies were selected, then 101 articles by reading the titles and after obtaining 28 by abstracts, of which, after reading in full, nine were elected to compose the sample. Finally, the interpretation of the results and writing of the article were performed. The study found that the association of metabolic syndrome with COVID-19 lead to a worse clinical outcome. The presence of factors that make up the metabolic syndrome are related to an increased likelihood of mechanical ventilation compliance, intensive care unit treatment, respiratory failure, pressure ulcers, and increased risk of mortality. On the other hand, it is shown that HDL can be used as a risk marker for severe COVID-19 outcomes and a triglycerides / HDL-c ratio as a prognostic marker of severity. Furthermore, a possible multimorbidity present in patients with advanced metabolic syndrome in this study corroborates the importance of controlling its components through educational actions, goals and therapeutic controls, through the multidisciplinary team, to provide a better quality of life.
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Copyright (c) 2023 Danielle Daga, Mônica Ester Krehnke Brueckheimer, Mylena Phillipps Cunha, Ana Clara Veiga Kuczera, Simone Basso, Daniele Fraccanabbia, Luis Gustavo Barzotto Walczewski, Kelly Cristina Daghetti, Bruna Dupont Meneghetti, Herbert Nagel Horst, Luciane Peter Grillo
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