Neonatal anemia may be detected in laboratory exams collected for other reasons in low and medium-risk neonates during the first week of life

Authors

  • Cristina Ortiz Sobrinho Valete Universidade Federal de São Carlos, São Carlos, SP. Brasil https://orcid.org/0000-0002-6925-4346
  • Fernanda Negrini Delgado Irmandade da Santa Casa de Misericórdia de São Carlos, São Carlos, SP
  • Julia Sato Fernandes Irmandade da Santa Casa de Misericórdia de São Carlos, São Carlos, SP
  • Esther Angelica Luiz Ferreira Universidade Federal de São Carlos, São Carlos, SP https://orcid.org/0000-0003-2582-9045
  • Renata Sayuri Ansai Pereira de Castro Universidade Federal de São Carlos, São Carlos, SP. Brasil https://orcid.org/0000-0002-4699-6398
  • Carolina Perez Montenegro Universidade Federal de São Carlos, São Carlos, SP. Brasil
  • Maria Clara Alves Pilati Universidade Federal de São Carlos, São Carlos, SP. Brasil
  • Carlos Henrique Araujo de Carvalho Universidade Federal de São Carlos, São Carlos, SP. Brasil https://orcid.org/0000-0002-6830-1585
  • Marco Otilio Duarte Rodrigues Wilde Universidade do Vale do Itajaí, Itajaí, SC. Brasil
  • Gleise Aparecida Moraes Costa Centro Universitário FMABC, São Bernardo do Campo, SP. Brasil https://orcid.org/0000-0001-9972-5607

DOI:

https://doi.org/10.11606/issn.1679-9836.v105i5e-219005

Keywords:

Anemia, Infant, newborn, Hematocrit, Erythrocyte indices

Abstract

Objectives: To analyze the frequency of anemia in low and medium-risk neonates who had blood withdraw for laboratory analysis during the first week of life. Methods: A prospective cross-sectional study, between September 2021 to June 2022, that included neonates greater than 34 weeks gestational age who were born in a tertiary hospital, were clinically stable and had blood withdraw for laboratory analysis during the first week of life (< 7 days). The outcome variable was anemia, defined as hemoglobin < 13.5 g/dL. Results: A hundred and fifty-one neonates with mean gestational age of 38,1 (SD 1.7) weeks, and mean birth weight 2,983 g (SD 541) were included. Six neonates (3.9%) had anemia and all of them were < 2 days of life. Neonates with fifth-minute Apgar scores < 7 had anemia more frequently (p =0.004). Conclusion: Anemia occurred in low and medium-risk neonates in their first week of life and was more frequent when the fifth-minute Apgar was < 7. These results highlight the need to observe all the hematological parameters in laboratory exams and begin anemia treatment as soon as possible in stable neonates.

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Author Biographies

  • Cristina Ortiz Sobrinho Valete, Universidade Federal de São Carlos, São Carlos, SP. Brasil

    Graduação em Medicina pela Universidade Federal do Rio de Janeiro (1992), mestrado em Saúde da Criança e do Adolescente pela Universidade Federal Fluminense (1999) e doutorado em Epidemiologia/Saúde Coletiva pela Universidade do Estado do Rio de Janeiro (2005). Atualmente é Professor Adjunto de Pediatria da Universidade Federal Fluminense e Vice-coordenadora do Programa de Pos-graduacao em Saude Materno Infantil, nivel Mestrado Profissional (2015). Tem experiência na área de Medicina e Saúde Coletiva/Gestão, com ênfase em Saúde Materno-Infantil, atuando principalmente nos seguintes temas: prematuro, terapia intensiva pediátrica, anemia, recém-nascido, crescimento e desenvolvimento. E especialista e tem vasta experiência em terapia intensiva pediátrica. Orienta trabalhos multiprofissionais nas áreas de Neonatologia, Terapia Intensiva Neonatal e Terapia Intensiva Pediatrica.

  • Fernanda Negrini Delgado, Irmandade da Santa Casa de Misericórdia de São Carlos, São Carlos, SP

    Resident of Pediatrics at São Carlos Holy House of Mercy.

  • Julia Sato Fernandes, Irmandade da Santa Casa de Misericórdia de São Carlos, São Carlos, SP

    Pediatrician at São Carlos Holy House of Mercy

  • Esther Angelica Luiz Ferreira, Universidade Federal de São Carlos, São Carlos, SP

    Professor at Medicine Department, São Carlos Federal University

  • Renata Sayuri Ansai Pereira de Castro, Universidade Federal de São Carlos, São Carlos, SP. Brasil

    Professor at Medicine Department, São Carlos Federal University

  • Carolina Perez Montenegro, Universidade Federal de São Carlos, São Carlos, SP. Brasil

    Medical student at São Carlos Federal University.

  • Maria Clara Alves Pilati, Universidade Federal de São Carlos, São Carlos, SP. Brasil

    estudante de Medicina da Universidade Federal de São Carlos

  • Carlos Henrique Araujo de Carvalho, Universidade Federal de São Carlos, São Carlos, SP. Brasil

    Medical student at São Carlos Federal University.

  • Marco Otilio Duarte Rodrigues Wilde, Universidade do Vale do Itajaí, Itajaí, SC. Brasil

    Professor of Pediatrics at University of Vale do Itajaí

  • Gleise Aparecida Moraes Costa, Centro Universitário FMABC, São Bernardo do Campo, SP. Brasil

    Professor of Pediatrics at FMABC University Center

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Published

2026-07-30

Issue

Section

Artigos Originais/Originals Articles

How to Cite

Valete, C. O. S., Delgado, F. N., Fernandes, J. S., Ferreira, E. A. L., Castro, R. S. A. P. de, Montenegro, C. P., Pilati, M. C. A., Carvalho, C. H. A. de, Wilde, M. O. D. R., & Costa, G. A. M. (2026). Neonatal anemia may be detected in laboratory exams collected for other reasons in low and medium-risk neonates during the first week of life. Revista De Medicina, 105(5), e-219005. https://doi.org/10.11606/issn.1679-9836.v105i5e-219005