Molecular signature of gliomas correlated to clinical epidemiological aspects of patients in follow-up at a reference center in São Paulo - Brazil - COMU 2023

Abstract

We have prepared a manuscript that represents our analysis regarding our study. Gliomas are more than 80% of all primary brain cancers and 24% of all brain tumors 1. In 2021, the new edition of WHO - Classification of Tumors of the Central Nervous System (WHO- CTCNS) 2 established genetic and molecular aspects to the analysis since they could be correlated to characteristics of tumor behavior and clinical-epidemiological features. However, there are few studies correlating molecular analysis to the clinical follow-up of patients in Brazil. We performed a preliminary, observational, prospective and descriptive study that aims to obtain and to compare clinical-epidemiological data to molecular markers of patients in follow-up at Central Hospital of Santa Casa de São Paulo (HC-ISCMSP).