Prevalence of mood disorders and anxiety in people with epilepsy: a systematic review
DOI:
https://doi.org/10.11606/issn.1679-9836.v103i4e-226358Keywords:
Epilepsy, Mood Disorders, Anxiety Disorders, PrevalenceAbstract
Background: Epilepsy is recognized as a group of chronic non-transmissible diseases that have recurrent epileptic seizures in common, and is associated with a greater predisposition to psychiatric comorbidities. Although mood and anxiety disorders frequently occur in people with epilepsy (PWE) and impair quality of life and treatment outcomes, current studies to investigate these comorbidities remain with unsatisfactory results for the epilepsy population in developing countries. Objectives: To describe the frequency of mood and anxiety disorders and the clinical and sociodemographic characteristics of people with epilepsy presenting with these disorders. Methods: Literature review in EMBASE, LILACS, PsycINFO, Pubmed, and Scielo databases. Cross-sectional studies published in the last 5 years in Portuguese and English language were included, and that evaluated comorbidities in individuals aged 18 years or older with a diagnosis of epilepsy facing the International League Against Epilepsy criteria. Results: Our search tracked 3,054 articles, of which 3047 were excluded for duplicate publication and for being incompatible with the topic due to eligibility criteria. The results found for psychiatric diagnoses ranged from 18% to 52.6% for the prevalence of mood disorders and 6.5% to 33.4% for anxiety disorders. Conclusion: This review found a higher prevalence of mood and anxiety disorders in PWE. Thus, physicians responsible for treating people with epilepsy should be aware of the increased chances of mood and anxiety disorders in this population in order to take an appropriate approach to these patients.
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