Role of Endoscopic Ultrasound in the Diagnosis of Frantz Tumor
DOI:
https://doi.org/10.11606/issn.1679-9836.v104iesp.e-235160Keywords:
Endoscopic ultrasound, Frantz Tumor, ß-cateninAbstract
The solid pseudopapillary tumor of the pancreas (SPTP), also known as Frantz tumor, is a rare lesion, accounting for less than 3% of neoplasms in this organ. It is more prevalent in women in their third decade of life and has a low malignant potential. The aim of this study is to report the case of a 27-year-old female patient who was found to have a lesion in the head of the pancreas on imaging exams. To better characterize the finding, a fine-needle aspiration (FNA) biopsy guided by endoscopic ultrasound (EUS) was performed. A hypoechoic, heterogeneous, lobulated, oval-shaped lesion measuring 44 mm × 37 mm was observed in the uncinate process, with regular contours, well-defined margins, and no involvement of adjacent vessels. Histopathological analysis revealed positivity for β-catenin (nuclear pattern), CD10, CD56, CD99 (dot-like), cyclin D1, TFE3, and androgen receptor, findings consistent with the diagnosis of Frantz tumor.
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Copyright (c) 2025 Wagner José da Silva, Luana Gabriela dos Santos, Vitória da Silva Castro, Evellin Souza Valentim dos Santos
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