Application of the nsofa score in preterm infants with suspected sepsis: a prognostic analysis
DOI:
https://doi.org/10.11606/issn.1679-9836.v105i2e-240034Keywords:
Very Low Birth Weight, Premature;, Organ Dysfunction Scores, Multiple Organ Failure; Neonatal sepsisAbstract
This study evaluated the application of the nSOFA score in preterm infants with suspected sepsis, aiming to identify associations with clinical outcomes. A prospective cross-sectional study was conducted between October 2022 and April 2023, including 41 preterm or very low birth weight newborns admitted to a neonatal intensive care unit. A significant association was found between catheter use and late-onset sepsis (p=0.015; OR=8.2), and between non-invasive mechanical ventilation and a lower occurrence of sepsis (p=0.001). In addition, nSOFA scores increased significantly from the first day of hospitalization to the moment of clinical suspicion (p=0.004), and higher scores were associated with an increased likelihood of death. These findings reinforce the potential role of the nSOFA score as an auxiliary tool for assessing disease severity and risk stratification in preterm infants with suspected sepsis, particularly in high-vulnerability clinical contexts.
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Copyright (c) 2026 RomuloTarga Pinto, Andressa Ribeiro dos Santos, Anna Leticia Baumel, Giullia Vercesi Beraldi, Cristina Terumy Okamoto, Maria Rigotto de Almeida, Julia Clenk Glodzinski
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