Duodeno-gastro-esophageal reflux (DGER), gastro-esophageal reflux disease (GERD

Abstract

The reflux of duodenal content through the pylorus into the stomach is a norma lphysiologic event occurring most commonly at night but also in post-prandial periods; and itoften caused symptoms and primary diseases. However, when it’s excessive, it may bepathologic and associated with gastritis, gastric ulcers, gastric carcinoma, dyspepsia andgastric-esophageal reflux disease (GERD). The incidence and prevalence of GERD are highand it represents the main gastroenterologic disease. The patophysiology of GERD’s complications, e.g. Barrett’s Esophagus, is also related, but after the introduce of bile monitoring,some of changes of esophagus’s epithelium have been attributed by duodenal-gastricesophageal reflux (DGER). Before introducing the bilirrubin monitoring, all techniques indetecting DRGE had poor sensitivity and specificity. Recently, a new fiberoptic spectrophtometer was developed which detects DGER, and a great of controversial issues have started in literature.Parallel, experimental studies have been developed and it seems that the excessive DGER has relationship with Barrett’s Esophagus and adenocarcinoma. The aim of this study is todiscuss the controversial of literature, and to evaluate all techniques in detecting DGER(advantages, disadvantages, sensibility and specificity). We’ll discuss the real importance ofDGER in Barrett’s Esophagus and your complications.