Gas necrosis and sepsis due to recreational ketamine use

Authors

  • Alexandre Sacchetti Bezerra Faculdade de Medicina do ABC, Santo André, São Paulo, Brazil; Hospital Israelita Albert Einstein, São Paulo, São Paulo, Brazil; Instituto de Infectologia Emilio Ribas, São Paulo, São Paulo, Brazil https://orcid.org/0000-0001-6870-7465
  • Carla Maria Pasquareli Vazquez Instituto de Infectologia Emilio Ribas, São Paulo, São Paulo, Brazil
  • Ana Carolina Troise Guilherme Faculdade Santa Marcelina, São Paulo, São Paulo, Brazil
  • Ana Beatriz Retamero Rodrigues Universidade Santo Amaro, São Paulo, São Paulo, Brazil
  • Murillo Barbosa Crivillari Instituto de Infectologia Emilio Ribas, São Paulo, São Paulo, Brazil
  • Wladimir Queiroz Instituto de Infectologia Emilio Ribas, São Paulo, São Paulo, Brazil

DOI:

https://doi.org/10.1590/

Keywords:

Ketamine., Sepsis, Necrosis, Tetanus, Amputation

Abstract

Although ketamine is an FDA-approved drug, its mechanism of action is not fully understood. Currently, there is an increase in its recreational use, causing irreparable social and physical damage. We report the case of a musician who developed sepsis due to gas necrosis in his arm after using veterinary ketamine purchased via the internet. Despite the amputation recommendation, it was possible to save the arm and preserve motor and sensory function. The scientific community, as well as the police and the government, must ponder the prescription, efficacy and safety of ketamine for medical treatments.

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Published

2025-02-14

Issue

Section

Case Report

How to Cite

Bezerra, A. S., Vazquez, C. M. P., Guilherme, A. C. T., Rodrigues, A. B. R., Crivillari, M. B., & Queiroz, W. (2025). Gas necrosis and sepsis due to recreational ketamine use. Revista Do Instituto De Medicina Tropical De São Paulo, 67, e09. https://doi.org/10.1590/