Application of anti-leptospira ELISA-lgM for the etiologic elucidation of meningitis

Authors

  • Marcos V Silva Emilio Ribas Institute of Infectology
  • Eide D Camargo Adolfo Lutz Institute
  • Luíza Batista Emilio Ribas Institute of Infectology
  • Adelaide J Vaz Adolfo Lutz Institute
  • Antonio W Ferreira Institute of Tropical Medicine of São Paulo
  • Paulo R.S. Barbosa Institute of Tropical Medicine of São Paulo

Keywords:

Leptospirosis, Meningitis and ELISA-IgM

Abstract

Leptospirosis is one of the causes of meningitis, although its importance is not well known. In the present study we contributed to this knowledge by demonstrating specific IgM class anti-leptospira antibodies by the immunoenzymatic method ELISA in 14.6% of cerebrospinal fluid (CSF) samples from 171 patients with meningitis considered to be of indeterminate etiology. The frequencies of positivity were similar in cases with predominance of polymorphonuclear or lymphomononuclear leucocytes in the CSF. Age distribution showed a predominance of the 5 to 15 year age range (72%), and sex distribution showed a predominance of males (68%). The authors discuss the contribution of this method to the etiologic elucidation of meningitis.

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Published

1996-04-01

Issue

Vol. 38 No. 2 (1996)

Section

Serodiagnosis

How to Cite

Silva, M. V., Camargo, E. D., Batista, L., Vaz, A. J., Ferreira, A. W., & Barbosa, P. R. (1996). Application of anti-leptospira ELISA-lgM for the etiologic elucidation of meningitis . Revista Do Instituto De Medicina Tropical De São Paulo, 38(2), 153-156. https://revistas.usp.br/rimtsp/article/view/29354