Genetic relationships among serogroup B: serotype 4 Neisseria meningitidis strains

Authors

  • Ana Paula S. LEMOS Adolfo Lutz Institute; Bacteriology Department; Division of Medical Biology
  • Claudio T. SACCHI Adolfo Lutz Institute; Bacteriology Department; Division of Medical Biology
  • Maria V. PAIVA Adolfo Lutz Institute; Bacteriology Department; Division of Medical Biology
  • Teresa I. YARA Adolfo Lutz Institute; Bacteriology Department; Division of Medical Biology
  • Carmo Elias A. MELLES Adolfo Lutz Institute; Bacteriology Department; Division of Medical Biology
  • Leonard W. MAYER Centers for Disease Control and Prevention; National Centers for Infectious Diseases; Division of Bacterial and Mycotic Diseases; Meningitis and Special Pathogens Branch

Keywords:

Neisseria meningitidis, Serogroup B, Serotype 4, Ribotyping, Strain differentiation

Abstract

We compared the results obtained by serotyping of PorB epitopes using an expanded panel of monoclonal antibodies (mAb) including mAb 7 and mAb 10, with results obtained by RFLP of rRNA genes (ribotyping). The purpose of this study was to assess the correlation between phenotypic- and genotypic- methods for typing N. meningitidis. The ribotypes obtained using ClaI or EcoRV endonucleases grouped the strains in seven and two different patterns, respectively. This additional characterization of PorB epitopes improved the correlation between these two methods of typing N. meningitidis.

Downloads

Download data is not yet available.

Downloads

Published

2001-06-01

Issue

Vol. 43 No. 3 (2001)

Section

Bacteriology

How to Cite

LEMOS, A. P. S., SACCHI, C. T., PAIVA, M. V., YARA, T. I., MELLES, C. E. A., & MAYER, L. W. (2001). Genetic relationships among serogroup B: serotype 4 Neisseria meningitidis strains . Revista Do Instituto De Medicina Tropical De São Paulo, 43(3), 119-124. https://revistas.usp.br/rimtsp/article/view/30506