The use of the antifungal agent miconazole as an inhibitor of Blastocystis hominis growth in Entamoeba histolytica/E. dispar cultures

Authors

  • Alessandra Queiroga Gonçalves Fundação Oswaldo Cruz; Departamento de Medicina Tropical; Laboratório de Doenças Parasitárias
  • João da Costa Viana Universidade Federal de Minas Gerais; Instituto de Ciências Biológicas; Departamento de Parasitologia
  • Edna Maria Pires Universidade Federal de Minas Gerais; Instituto de Ciências Biológicas; Departamento de Parasitologia
  • Márcio Neves Bóia Fundação Oswaldo Cruz; Departamento de Medicina Tropical; Laboratório de Doenças Parasitárias
  • José Rodrigues Coura Fundação Oswaldo Cruz; Departamento de Medicina Tropical; Laboratório de Doenças Parasitárias
  • Edward Félix Silva Universidade Federal de Minas Gerais; Instituto de Ciências Biológicas; Departamento de Parasitologia

Keywords:

Blastocystis hominis, Miconazole, Entamoeba histolytica, Entamoeba dispar, Culture

Abstract

In regions with high prevalence, Blastocystis hominis is frequently found in association with Entamoeba histolytica/E. dispar in xenic cultures. Its exacerbated growth is often superimposed on the growth of amebas, thus impeding the continuation of the amebas in the culture, within a few generations. The present study reports on the excellent efficacy (100%) of the antifungal agent miconazole in eliminating B. hominis from cultures of E. histolytica/E. dispar, thereby maintaining the integrity of the trophozoites of the amebas. Nystatin presented low efficacy (33.3%).

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Published

2007-06-01

Issue

Vol. 49 No. 3 (2007)

Section

Brief Communication

How to Cite

Gonçalves, A. Q., Viana, J. da C., Pires, E. M., Bóia, M. N., Coura, J. R., & Silva, E. F. (2007). The use of the antifungal agent miconazole as an inhibitor of Blastocystis hominis growth in Entamoeba histolytica/E. dispar cultures . Revista Do Instituto De Medicina Tropical De São Paulo, 49(3), 201-202. https://revistas.usp.br/rimtsp/article/view/31091