Dynapenic Abdominal Obesity, Dynapenia, and Abdominal Obesity in Patients Undergoing Hemodialysis
DOI:
https://doi.org/10.11606/issn.2176-7262.rmrp.2025.212381Keywords:
Chronic kidney disease, Handgrip strength, Waist circumferenceAbstract
Introduction: Dynapenic abdominal obesity (DAO), the co-occurrence of abdominal obesity and low muscle strength, is prevalent among older adults and consequently common among patients with chronic kidney disease (CKD) undergoing hemodialysis. However, evidence on the association between DAO and gait slowness in this population remains limited. Objectives: (i) To investigate the prevalence of abdominal obesity (AO), dynapenia (D), and DAO phenotypes among CKD patients on hemodialysis; (ii) To examine the relationship between slowness and the AO, D, and DAO phenotypes. Methods: This cross-sectional study was conducted at a nephrology center and included male and female patients aged ≥50 years undergoing hemodialysis. Sociodemographic and clinical data were collected. Muscle strength was assessed using handgrip dynamometry (<26/16 kg for men/women, respectively). AO was defined by increased waist circumference (WC) (>88 cm for women, >102 cm for men). Slowness was evaluated using gait speed (cutoff ≤0.8 m/s). DAO was defined as the combination of increased WC and low muscle strength. A significance level of p<0.05 was adopted for statistical analyses. Results: The study included 94 patients (mean age 62.1±9.2 years), predominantly male (73.4%) and older adults (52.1%). Patients with DAO were significantly weaker and slower compared to those with non-AO/non-D and AO phenotypes (p<0.001). The overall prevalence of DAO was 13.8%, with the highest proportion of slowness observed among DAO patients (69.2%). Conclusion: Patients with the DAO phenotype exhibit slower gait and lower strength than those with AO or without abdominal obesity and dynapenia.
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