Linear lichen planus after COVID-19 vaccination
DOI:
https://doi.org/10.11606/issn.2176-7262.rmrp.2025.227774Palabras clave:
Lichen planus, COVID-19, Drug-related side effects and adverse reactions, Vaccination, Case reportsResumen
The side effects of COVID-19 vaccines are increasingly being documented, including cutaneous manifestations. In this case report, we describe a 49-year-old female patient who developed pruritic, violaceous, linear lesions on her left lower limb following COVID-19 vaccination. A biopsy confirmed the diagnosis of linear lichen planus, a rare variant of the disease, which was treated with topical clobetasol, resulting in a good response. Although lichen planus has an unknown etiology, COVID-19 vaccination may act as a triggering factor, possibly due to an intense inflammatory response. Monitoring adverse effects is crucial to minimize patient discomfort and maintain confidence in mass vaccination.
Descargas
Referencias
1. Wang H, Paulson KR, Pease SA, Watson S, Comfort H, Zheng P, et al. Estimating excess mortality due to the COVID-19 pandemic: a systematic analysis of COVID-19-related mortality, 2020–21. Lancet. 2022;399(10334):1513–36.
2. Merhy R, Sarkis AS, Kaikati J, El Khoury L, Ghosn S, Stephan F. New-onset cutaneous lichen planus triggered by COVID-19 vaccination. J Eur Acad Dermatology Venereol. 2021;35(11):e729–30.
3. Kroumpouzos G, Paroikaki ME, Yumeen S, Bhargava S, Mylonakis E. Cutaneous Complications of mRNA and AZD1222 COVID-19 Vaccines: A Worldwide Review. Microorganisms. 2022;10(3).
4. Mcmahon DE, Amerson E, Rosenbach M, Lipoff JB. Cutaneous reactions reported after Moderna and Pfizer COVID-19 vaccination: A registry-based study of 414 cases. J Am Acad Dermatol. 2021;85(1):46–55.
5. Zou H, Daveluy S. Lichen planus after COVID-19 infection and vaccination. Arch Dermatol Res [Internet]. 2023;315(2):139–46. Available from: https://doi.org/10.1007/s00403-022-02497-y
6. Kato J, Kamiya T, Handa T, Kobayashi E, Hida T, Yamashita T, et al. Linear lichen planus after COVID-19 vaccination. Australas J Dermatol. 2022;63(4):e385–7.
7. Williner ME, Inza M, Garay IS, Kurpis M, Lascano AR. Liquen plano lineal Blashkoide, reporte de 2 casos. Rev argent dermatol [Internet]. 2019;100(4):108–9. Available from: https://rad-online.org.ar/2020/01/28/liquen-plano-lineal-blashkoide-reporte-de-2-casos/
8. Castillo JG, Goma FJ de la T, Aguirre AS. Lichen planus after SARS-CoV-2 infection treated with lopinavir/ritonavir. Med Clin (Barc). 2021;156:468–9.
9. Lehman JS, Tollefson MM, Gibson LE. Lichen planus. Int J Dermatol. 2009;48(7):682–94.
10. Herzum A, Burlando M, Molle MF, Micalizzi C, Cozzani E, Parodi A. Lichen planus flare following COVID-19 vaccination: A case report. Clin Case Reports. 2021;9(12):10–2.
11. Diab R, Araghi F, Gheisari M, Kani ZA, Moravvej H. Lichen planus and lichen planopilaris flare after COVID-19 vaccination. Dermatol Ther. 2022;35(3):e15283.
Descargas
Publicado
Número
Sección
Licencia
Derechos de autor 2026 Isabela Sella Sartorelli, Marilda Aparecida Milanez Morgado de Abreu
Esta obra está bajo una licencia internacional Creative Commons Atribución 4.0.
