Use of mutagenicity tests to assess occupational exposure
DOI:
https://doi.org/10.11606/issn.2317-2770.v12i1-2p15-21Keywords:
Cytogenetics. Mutagenicity tests. Micronucleus tests. Occupational exposure. Occupational health, bus driver.Abstract
The cytogenetic tests are important biomarkers of exposure to evaluate mutagenic effects of external agents and its metabolites in the internal cell environment. These tests have been used in the biological monitoring of populations exposed to genotoxic substances, mainly in the occupational area. The frequency micronucleous, evaluated in 24 bus drivers of the city of São Paulo, was higher than the frequency observed in a control group of 13 bus drivers who were away from their jobs for more than six months. In spite of the low number of individuals, the partial results of this research that was performed with patients who attended the Occupational Health Service of the HCFMUSP, suggest an expansion of this project to evaluate a possible inclusion of periodic tests protocol for these professionals in the future.
Downloads
References
Downloads
Published
Issue
Section
License
Autores que publicam nesta revista concordam com os seguintes termos:
- Autores mantém os direitos autorais e concedem à revista o direito de primeira publicação, que permite o compartilhamento do trabalho com reconhecimento da autoria e publicação inicial nesta revista.
- Autores têm autorização para assumir contratos adicionais separadamente, para distribuição não-exclusiva da versão do trabalho publicada nesta revista (ex.: publicar em repositório institucional ou como capítulo de livro), com reconhecimento de autoria e publicação inicial nesta revista.
