Cardiovascular effects of midazolam in levomepromazine premedicated dogs

Authors

  • Gladys Bastos de Castro Universidade Estadual Paulista, Faculdade de Medicina Veterinária e Zootecnia, Botucatu, SP
  • Flavio Massone Universidade Estadual Paulista, Faculdade de Medicina Veterinária e Zootecnia, Botucatu, SP
  • Antonio José de Araújo Aguiar Universidade Estadual Paulista, Faculdade de Medicina Veterinária e Zootecnia, Botucatu, SP
  • Stélio Pacca Loureiro Luna Universidade Estadual Paulista, Faculdade de Medicina Veterinária e Zootecnia, Botucatu, SP
  • Silvia Renata Gaido Universidade Estadual Paulista, Faculdade de Medicina Veterinária e Zootecnia, Botucatu, SP

DOI:

https://doi.org/10.11606/issn.1678-4456.bjvras.1992.51991

Keywords:

Midazolam, Anaesthesia of dogs, Cardiovascular system, Levomepromazine

Abstract

Experiments were performed on ten mongrel dogs with 10-18 kg body weight. They received levomepromazine 1.0 mg/kg body weight, I.V. as premedication, and 15 minutes later, midazolam was given in dosage of 2.0 mg/kg body weight intravenously. The result showed moderat increase on respiratory rate and decrease heart rate after 15 minutes and increase heart rate after 30 minutes. Mean and sistolic arterial pressure decreased significantly (p<0.05) but without clinical importance, remained in the physiologic range. Hipnosis duration was less than 20 minutes and at 30 minutes the dogs awaked and they tried to walk.

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Published

1992-12-02

Issue

Vol. 29 No. 2 (1992)

Section

ANIMAL PATHOLOGY

License

The journal content is authorized under the Creative Commons  BY-NC-SA  license (summary of the license: https://creativecommons.org/licenses/by-nc-sa/4.0 | full text of the license: https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode) 

How to Cite

1.
Castro GB de, Massone F, Aguiar AJ de A, Luna SPL, Gaido SR. Cardiovascular effects of midazolam in levomepromazine premedicated dogs. Braz. J. Vet. Res. Anim. Sci. [Internet]. 1992 Dec. 2 [cited 2024 Nov. 8];29(2):251-6. Available from: https://revistas.usp.br/bjvras/article/view/51991