Efficiency test for foot and mouth disease vaccine. II. Relationship between the C Index in guinea pigs and the Mouse Protection Index

Authors

  • Ernani Ibirá Gonçalves Universidade Estadual Paulista, Faculdade de Ciências Agrárias e Veterinárias, Jaboticabal, SP.
  • Aramis Augusto Pinto Universidade Estadual Paulista, Faculdade de Ciências Agrárias e Veterinárias, Jaboticabal, SP.

DOI:

https://doi.org/10.11606/issn.1678-4456.bjvras.1994.52046

Keywords:

Foot and mouth disease, Vaccine, C Index, Mouse Protection Index

Abstract

The efficiency of six foot and mouth disease vaccines was examined by the Mouse Protection Index and C Index tests using 15 or more guinea pigs per viral dilution for titration. A good correlation and high significance were obtained between the tests. The value of the Mouse Protection Index was approximately double the C Index value. Thus, in view of its low cost and easy execution due to the exclusive use of mice, the Mouse Protection Index can be recommended for testing the efficiency of foot and mouth disease vaccines, especially when a large number of tests is needed.

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Published

1994-03-01

Issue

Vol. 31 No. 1 (1994)

Section

PREVENTIVE VETERINARY MEDICINE

License

The journal content is authorized under the Creative Commons  BY-NC-SA  license (summary of the license: https://creativecommons.org/licenses/by-nc-sa/4.0 | full text of the license: https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode) 

How to Cite

1.
Gonçalves EI, Pinto AA. Efficiency test for foot and mouth disease vaccine. II. Relationship between the C Index in guinea pigs and the Mouse Protection Index. Braz. J. Vet. Res. Anim. Sci. [Internet]. 1994 Mar. 1 [cited 2025 Apr. 12];31(1):31-4. Available from: https://revistas.usp.br/bjvras/article/view/52046