Failure of passive immunity transfer in crossbred lambs (Santa Inês x Dorper) and proteinogram study from birth until waned

Abstract

It was analyzed the occurrence of the failure of passive transfer (FTIP) of the immunity 45 born lambs of healthy and pluriparous ewes. These animals were accompanied from the birth to the wean (90 days), when clinical evaluations were accomplished, hemogram, determination of total serum proteins and their electrophoretic fractions, 24-72h after the birth, to the 7, 15, 30, 60 and 90 days of age (at the same time of the wean). Adopting the cut point for total serum proteins of the order of 4.5g/dL, it was obtained the occurrence of FTIP of 24.4% (11 animals). The lambs with FTIP presented lowers values (p<0.05) of serum proteins, albumin, alpha-globulin, beta-globulin 1 and gamma globulins when compared to the 34 animals that have no FTIP. However, from 7th days of life it was not observed significant differences of these variables between groups, indicating the occurrence of a process of active production of proteins by group FTIP.