DA INEFICÁCIA DA ADMINISTRAÇÃO DA PROCAÍNA, SULFADIAZINA, ÁCIDO p-AMINOBENZÓICO E ÁCIDO ·p-AMINOBENZÓICO OXIDADO, NA SOBREVIDA DE CAMUNDONGOS FÊMEAS

Abstract

By comparing the survival of 5 groups of mice wich received subcutaneous doses of a-~-solution of procaine, sulfadiazine, p-aminobenzoic acid, oxidated p-aminobenzoic acid, and physiologicélil serum, three times a week, using Kruskal Wallis17 one way analyses of variance by ranks, we obtained a H = 2,34; each of these groups had 50 animais. By comparing the survival of one control group to the survival of a procaine group, using the Mann-Whitney U test we obtained a z = 0,627; each group included 30 new animais besides the 50 already mentioned. We conclude that the survival of the animais belonging to the four groups used in the experiment was not different from the survival of the control group. We suggest further experimentations and careful clinicai studies before any conclusions can be drawn about the action of these drugs in the life lengthening of men and laboratory animais.