A great simulator in clinical practice: mononeuritis multiplex in HIV infection

Authors

  • José Pedro Soares Baima Universidade de São Paulo (USP), Hospital das Clínicas, Faculdade de Medicina, Departamento de Neurologia, São Paulo, SP, Brasil https://orcid.org/0000-0003-2708-1181
  • Beatriz Carneiro Gondim Silva Universidade de São Paulo (USP), Hospital das Clínicas, Faculdade de Medicina, Departamento de Neurologia, São Paulo, SP, Brasil https://orcid.org/0009-0003-4375-8700
  • Vanessa Lopes Vieira Universidade de São Paulo (USP), Hospital das Clínicas, Faculdade de Medicina, Departamento de Medicina Interna, São Paulo, SP, Brasil https://orcid.org/0009-0009-0348-8893
  • Luiz Pedro Meireles Universidade de São Paulo (USP), Hospital das Clínicas, Faculdade de Medicina, Departamento de Medicina Interna, São Paulo, SP, Brasil https://orcid.org/0009-0001-8201-9092
  • Milton Hideaki Arai Universidade de São Paulo (USP), Hospital das Clínicas, Faculdade de Medicina, Departamento de Medicina Interna, São Paulo, SP, Brasil https://orcid.org/0009-0007-5609-2740
  • Angelina Maria Martins Lino Universidade de São Paulo (USP), Hospital das Clínicas, Faculdade de Medicina, Departamento de Neurologia, São Paulo, SP, Brasil https://orcid.org/0000-0001-7109-8365

DOI:

https://doi.org/10.4322/acr.2024.493

Keywords:

Biopsy, HIV, Mononeuropathies, Vasculitis

Abstract

HIV infection is a chameleon, mimicking several diseases. Herein, we report a previously healthy 39-year-old woman who, over 2 months, developed arthritis, weight loss, and confluent multiple mononeuropathy. Extensive laboratory investigation showed positive serology for HIV, with a CD4 count of 100 cells, and necrotizing vasculitis on a nerve biopsy not associated with CMV co-infection, allowing the diagnosis of polyarteritis nodosa-like vasculitis in an HIV-infected patient. Apart from the infection, HIV-related autoimmunity can affect any organ and contribute to the complexity of the clinical presentation of HIV infection.

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Published

2024-07-26

Issue

Section

Clinical Case Report

How to Cite

Baima, J. P. S., Silva, B. C. G., Vieira, V. L., Meireles, L. P., Arai, M. H., & Lino, A. M. M. (2024). A great simulator in clinical practice: mononeuritis multiplex in HIV infection. Autopsy and Case Reports, 14, e2024493. https://doi.org/10.4322/acr.2024.493