Analysis of antimicrobials' consumption profile in a University Hospital of Western Paraná, Brazil
DOI:
https://doi.org/10.1590/S1984-82502009000200015Keywords:
Medicines^i1^sDefined Daily Do, Medicines^i1^sutilizat, Antimicrobials^i1^sconsumpt, PharmacoepidemiologyAbstract
The objective of this study was to analyze the variation in antimicrobials' consumption and the costs related to their use at a University Hospital between 1999 and 2004. The annual consumption of nine antimicrobials, expressed in DDD/100 patients-day, and the direct costs with their acquisition were evaluated. Analysis of variance and regression techniques were used to compare data, considering a significance level of 5%. The most consumed antimicrobials were amikacin and ceftriaxone. In general, antimicrobials consumption, expressed in DDD/100 patients-day, increased from 9.21 in 1999 to 25.08 in 2004 (p<0.0001). When analyzing antimicrobial consumption as related to specific hospital units, the ICU showed the highest consumption followed by Chemotherapy and Medical Clinical units, respectively. In addition, the number of patients-day increased from 2671/month in 1999 to 3502/month in 2004, p<0.0001. As a consequence, total expenditure with antimicrobials increased from R$ 98.89 per 100 patients-day in 1999 to R$ 731.26 in 2004, p<0.0001. Between 1999 and 2004 significant increases in both consumption and financial expenditure with antimicrobials were observed.Downloads
Download data is not yet available.
Downloads
Published
2009-06-01
Issue
Section
Original Papers
License
All content of the journal, except where identified, is licensed under a Creative Commons attribution-type BY.
The on line journal has open and free access.
How to Cite
Analysis of antimicrobials’ consumption profile in a University Hospital of Western Paraná, Brazil . (2009). Brazilian Journal of Pharmaceutical Sciences, 45(2), 295-302. https://doi.org/10.1590/S1984-82502009000200015