Spectroscopic and thermal characterization of alternative model biomembranes from shed skins of Bothrops jararaca and Spilotis pullatus

Authors

  • André Rolim Baby University of São Paulo; Faculty of Pharmaceutical Sciences; Department of Pharmacy
  • Áurea Cristina Lemos Lacerda University of São Paulo; Faculty of Pharmaceutical Sciences; Department of Pharmacy
  • Fernanda Daud Sarruf University of São Paulo; Faculty of Pharmaceutical Sciences; Department of Pharmacy
  • Claudinéia Aparecida Sales de Oliveira Pinto University of São Paulo; Faculty of Pharmaceutical Sciences; Department of Pharmacy
  • Vladi Olga Consiglieri University of São Paulo; Faculty of Pharmaceutical Sciences; Department of Pharmacy
  • Cristina Helena dos Reis Serra University of São Paulo; Faculty of Pharmaceutical Sciences; Department of Pharmacy
  • Maria Valéria Robles Velasco University of São Paulo; Faculty of Pharmaceutical Sciences; Department of Pharmacy
  • Yoshio Kawano University of São Paulo; Institute of Chemistry; Department of Fundamental Chemistry
  • Telma Mary Kaneko University of São Paulo; Faculty of Pharmaceutical Sciences; Department of Pharmacy

DOI:

https://doi.org/10.1590/S1984-82502009000300006

Keywords:

Biomembrane^i1^salternative mod, Bothrops jararaca^i1^ss, Bothrops jararaca^i1^squalitative characterizat, Spilotis pullatus^i1^ss, Spilotis pullatus^i1^squalitative characterizat, Human stratum corneum^i1^ssimil

Abstract

Recently, there has been an interest in the use of shed snake skin as alternative model biomembrane for human stratum corneum. This research work presented as objective the qualitative characterization of alternative model biomembranes from Bothrops jararaca and Spilotis pullatus by FT-Raman, PAS-FTIR and DSC. The employed biophysical techniques permitted the characterization of the biomembranes from shed snake skin of B. jararaca and S. pullatus by the identification of vibrational frequencies and endothermic transitions that are similar to those of the human stratum corneum.

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Published

2009-09-01

Issue

Section

Original Papers

How to Cite

Spectroscopic and thermal characterization of alternative model biomembranes from shed skins of Bothrops jararaca and Spilotis pullatus . (2009). Brazilian Journal of Pharmaceutical Sciences, 45(3), 423-428. https://doi.org/10.1590/S1984-82502009000300006