Pyroligneous extracts with therapeutic action
A technological prospect
DOI:
https://doi.org/10.1590/Keywords:
Pyroligneous extract, Patent, PharmacologyAbstract
The Pyroligneous extract is a product from the combustion of plant biomass with applications in the fields of health, industrial chemistry, and agriculture. The discovery of new molecules with therapeutic potential and of natural origin continues to be one of the great challenges for research centres around the world. The following work aims to analyze, through a technological prospection, the use of pyroligneous extracts for therapeutic purposes. To carry out the study, searches were carried out in documents deposited in Brazil, Europe, and the United States and searched on platforms specialized in patents. The number of inventions using pyroligneous extract with therapeutic applications is still quite small, however, innovations have been observed for the treatment of diseases of great clinical relevance such as cancer and hypertension. The systematic mapping of innovations is of great importance for the development of new technologies.
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Balliano TL, Bispo MD, Soletti JI, Vieira WT, Amaral GV, Farias MB; Carvalho SHV, et al. Pyroligneous extract for the treatment of microbial infections. Patent: BR 1020200137514 A2. Federal University of Alagoas; 2022.
Boulard D, Graham R, Freel B. Thermal Extraction Method for Producing a Taxane Extract. Patent: EP2007744 B1. Pharmatherm Chemicals Inc; 2017.
Campos D. Technical Information on Pyroligneous Extract. Technical Circular No. 177. Embrapa Temperate Climate. 2018.
Canfeng G. Medicinal liquor for treating arthritis. Patent: CN 10519445 A. Gong Canfeng; 2015.
Casanova LM, Costa SS. Synergistic Interactions in Natural Products: Therapeutic Potential and Challenges. Rev Virtual Quim. 2017;9(2):575-595.
Casanova S, Vasconcelos J, Miranda A, Mansinho K, Fernandes C. Non-Biologic Systemic Therapies Associated Infections in Dermatology: How to Prevent. J Port Soc Dermatol Venereol. 2021;79(2):121-128.
Chiamenti L, Fratta L, Picoli S, Kreutz O, Morisso F, Moura A. Antibacterial action of pyroligneous liquor on coliforms. Revista Conhecimento Online. 2016;2(8):47-54.
Chuah C, Loh S. Hygiene Wash. Patent: WO2019/221593 A1. Diamond Star Global. SDN. BHD; 2019.
Chuah, C, Loh, S. Personal care products and their manufacturing methods. Patent: KR 20200143725 A. Diamond Star Global Sdn Bhd; 2020.
Dawei, H. External-application Du-channel-dredging bonesetting liquid and preparation method thereof. Patent: CN 106039052 A. Huan Dawei; 2016.
Dian PHM, Joppert PER, Kozusny-Andreani DI, Soares VE, Belo MAA, Melo GMP, Pacheco MD. Antimicrobial activity of organic acids with and without plant extract in the in vitro control of Escherichia Coli and Salmonella Typhi. ARS Veterinária. 2020;36(4):236-241.
Etienne R, Viegas FPD, Viegas C. Pathophysiological aspects of inflammation and drug design: an updated overview. Rev Virtual Quim. 2020;13:167-191.
Feldmann PR. Africa and South America: The future passes bybiodiversity. Estudos Avançados. 2021;35(102):111-123.
Félix CRO, Junior AFA, Freitas CC, Pires CAM, Teixeira V, Frety R. et al. Fast pyrolysis of eucalyptus biomass in the presence of Al-MCM-41 catalyst. Revista Matéria. 2017;22:1-11.
Gyu P. Components for soap containing medicinal herbs. Patent: KR 20170023234. Park Ok Gyu; 2017.
Haixia W, Zhong SI, Peitong H, Zang L, Hayun L, Jianshe H, et al. Composition for treating acute and chronic pharyngitis. Patent: CN 105708827A. Xinji Yuan Xiang Green Energy Tech Co Ltd; 2016a.
Haixia W, Zhong SI, Peitong H, Zang L, Hayun L, Jianshe H, et al. Composition for treating bromhidrosis. Patent: CN 105616393 A. Xinji Yuan Xiang Green Energy Tech Co Ltd; 2016b.
Haixia W, Zhong SI, Peitong H, Zang L, Hayun L, Jianshe H, et al. Composition for treating hyperostosis. Patent: CN 105663377 A. Xinji Yuan Xiang Green Energy Tech Co Ltd; 2016c.
Haixia W, Zhong SI, Peitong H, Zang L, Hayun L, Jianshe H, et al. Composition for treating oral ulcers. Patent: CN 105687248 A. Xinji Yuan Xiang Env Prot Energy Tech Co Ltd; 2016d.
Haixia W, Zhong SI, Peitong H, Zang L, Hayun L, Jianshe H, et al. Composition for treating wart. Patent: CN 105663175 A. Xinji Yuan Xiang Green Energy Tech Co Ltd; 2016e.
Haixia W, Zhong SI, Peitong H, Zang L, Hayun L, Jianshe H, et al. Mouthwash. Patent: CN 105560079 A. Xinji Yuan Xiang Green Energy Tech Co Ltd; 2016f.
Haixia W, Zhong SI, Peitong H, Zang L, Hayun L, Jianshe H, et al. Tinea pedis treatment solution. Patent: CN 105497079A. Xinji Yuan Xiang Green Energy Tech Co Ltd; 2016g.
Hiroshi M, Shinya Y, Toru K. Low Formaldehyde Pyroligneous. Patent: JP 2018203852 A. Aomori Prefectural Industrial Tech Research Center; 2018.
Hiroyoshi I, Ayako M. Cox-2 inhibitor. Patent: JP 2015199717 A. Inoue Hiroyoshi, Mori Ayako; 2015.
Ho C. Composition for improving atopic skin. Patent: KR 20170041149 A. Choi Yong Ho; 2017.
Ho W. Clinical Usage of Pyroligneous Liquor. Patent: WO2020/204391 A2. Wang Sung Ho; 2020.
Hoffmann MG, Coral E, Jara R. Relationships between R&D, patents and exports in actively innovative brazilian companies. B Magazine; 2014; 19(3):75-90.
Ibrahim D, Kassim J, She-Hong L, Rusli W. Efficacy of pyroligneous acid from Rhizophora apiculata on pathogenic Candida albicans. J of Applied Pharm Sci. 2013; 3(07):07-13.
INPI - National Institute of Industrial Property. Patent Classification, 2015. [cited 2022 Mar 10]. Available from: Available from: https://www.gov.br/inpi/pt-br/servicos/patentes/classificacao
» https://www.gov.br/inpi/pt-br/servicos/patentes/classificacao
INPI - National Institute of Industrial Property. Trademark Manual: granting, maintenance and yermination of registration, 2023. [cited 2023 Mar 16]. Available from: Available from: http://manualdemarcas.inpi.gov.br
» http://manualdemarcas.inpi.gov.br
Joon M, Sang Y. Deodorizing Shoe Insoles with Built-in Filter. Patent: KR 20160000145 A. Daeduk College Iacf; 2016.
Jun P. Manufacturing Method for Massager and Itself. Patent: KR 20160040924 A. Pae Jung Jun; 2016.
Ki PD, Bum PH. Complex ferment extract and manufacturing method thereof. Patent: KR 20140021327 A. Park Dong Ki, Park Hoi Bum; 2014.
Ki YS. Pharmaceutical composition for preventing or improving nose’s disease and sleepiness. Patent: KR 20150128169 A. Yoo Sang Ki; 2015.
Mitsuo H. Therapeutic agent for skin and production method thereof. Patent: JP 2020152709 A. Toso Eco Clean; 2020.
Mueller LT, Oliveira KV, Morisso FDP, Kunst SR, Carone CLP, Oliveira CT. Influence of the concentration of acetic acid present in the pyroligneous liquor on the anodization of niobium. Tecnol Metal Mater Min. 2021;18:1-9.
Neris RR, Magnabosco P, Amaral PA, Ribeiro MA, Ribeiro MA; Anjos ACY. Pain induction by chemotherapy medication docetaxel in women with breast cancer. Acta Paul Enferm. 2016;29(4):397-404.
Paulino JF, Afonso JC. From fame to ostracism: eight reagents that left the laboratory environment. Quim Nova. 2021;44(10):1395-1403.
Pinto BCM, Simões FA, Moreira, GF, Castro MM, Coscarelli LP, Castro MB, et al. Corticotherapy: adverse eye manifestations. EJCH. 2020;12(11):1-7.
Qiuyan S, Sun X, Shuren Y, Yunxiang L, Yanling W, Fang W, et al. Pyroligneous liquor-containing pet dermatosis therapeutic agent and preparation method thereof. Patent: CN 112402370 A. Shandong Susha Ecological Dev Co Ltd, Shandong Vocational Animal Science & Veterinary College; 2021.
Santiago AR, Andrade AM. Carbonization of residues from the mechanical processing of eucalyptus wood. Ciência Florestal. 2005;15:1-7.
Schnitzer, JA, Su MJ, Ventura MU. Faria RT. Doses of pyroligneous extracts in orchid cultivation. Rev Ceren Viçosa. 2015;62:101-106.
Shengchun H, Xiaohua H, Yitao W. Direct-injection spray containing apple branch pyroligneous liquor and preparation method thereof. Patent: CN 111920863A. Northwest A&F Univ, Shaanxi Jinjie Bioenergy Co Ltd; 2020.
Shinya Y, Toru K. Antifungal and Antiyeast Agent Containing Novel Pyroligneous Acids as Active Ingredient. Patent: JP 2018118955 A. Aomori Prefectural Industrial Tech Research Center; 2018.
Silva DW, Canepele E, Writzl TC, Steffler AD Stein JES, War D, et al. Effect of pyroligneous extract on early development of maize and bean plants. Rev Electronic Scientific from UERGS. 2021;7:93-102.
Silva JF, Figueredo KA, Carvalho MGFMC. Natural products for the treatment of leishmaniasis: a technological prospect. Rev Cuban de Farm. 2016;50(02):1-13.
Silva LSS, Santos JS. Applicability of vegetable oils in hair tonics: a review. Reseach, Society and Development. 2021;10(15):1-12.
Siqing Z. Antibacterial liquid containing pyroligneous composition and preparation method of antibacterial liquid. Patent: CN 111742936 A. Tangshan Jinhai New Mat Co., Ltd; 2020.
Souza JLS, Guimaraes VBS, Campos AD, Lund RG. Antimicrobial potential of pyroligneous extracts - a systematic review and technological prospecting. Braz J Microbiol. 2018; 49:128-139.
Vieira PR, Mokochinski, JB, Palma LC, Lidoino VG, Halasz MRT. Chemical characterization of the pyroligneous extract from carbonization. In: XX Brazilian Congress of Chemical Engineering.19 - 22 October 2014; Florianopolis / SC.
WHO - World Health Organization. History of the COVID-19, 2022. [cited 2022 Jun 10]. Available from: Available from: https:// www.paho.org/pt/covid19/historico-da-pandemia-covid-19
» https:// www.paho.org/pt/covid19/historico-da-pandemia-covid-19
WIPO - World Intellectual Property Organization. World Intellectual Property Indicators: an annual benchmark survey of IP activity around the world, 2022. [cited 2023 Apr 20]. Available from: Available from: https://wipo.int
WIPO - World Intellectual Property Organization. World Intellectual Property Indicators: Even with a challenging scenario in 2022, international patent applications continue to rise, 2023. [cited 2023 Apr 20]. Available from: Available from: https://wipo.int
WIPO - World Intellectual Property Organization. World Intellectual Property Indicators: patent applications, trademarks, Industrial designs reach records in 2018, 2019. [cited 2022 Mar 16]. Available from: Available from: https://wipo.int
Wu L. Health-care and sleep-aid composition, foot patch using the same and preparation method of foot patch. Patent: CN 109999073 A. Hangzhou Bixin Biotechnology Co Ltd; 2019.
Xinsheng C, Xiang W. Traditional chinese medicine for treating rheumatoid arthritis. Patent: CN 104367754 A. Cao Xinsheng; Wang Xiang; 2015.
Xueqi J, Haixia W, Jianshe H. Haemorrhoids treatment composition. Patent: CN 105748486 A. Xinji Yuan Xiang Green Energy Techology Co Ltd; 2016.
Yong Y. Multifunctional health product composition. Patent: CN 105831646 A. Ye Yong; 2016.
Yongjun L; Oral liquid for treating hypertension. Patent: CN 104083471 A. Li Yongjun; 2014a.
Yongjun L; Preparation method of novel chinese herbal medicine pyroligneous liquor-containing anticancer drug. Patent: CN 104083470 A. Li Yongjun; 2014b.
Zhixin H, Chao C. Pyroligneous foot antibacterial product and preparation method thereof. Patent: CN 112190626 A. Tangshan Xinyanuo Biotechnology Co Ltd; 2021.
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