Reasons for vaccination hesitancy against covid-19 in children and young people: a qualitative‒quantitative study
DOI:
https://doi.org/10.1590/s2175-97902025e24454Keywords:
Vaccination Hesitancy, Vaccine, COVID-19Abstract
The COVID-19 pandemic has had a devastating socioeconomic impact and reignited the debate on vaccination and the hesitancy to vaccinate children and young people. This study sought to understand the reasons related to the behaviour of parents in vaccinating their children aged 5 to 17 years against COVID-19 with currently available vaccines; this study was conducted from June 2022 to July 2022. This work was a cross-sectional, descriptive, and observational study with a qualitative‒quantitative approach. The individuals in the sample had a mean age of 12 years, were mostly public school students, did not have COVID-19, and had a complete vaccination card. Parents who had vaccinated their children reported understanding that vaccination supports immunity, whereas those who had not vaccinated their children did not trust the COVID-19 vaccine. The ability to recognize fake vaccine related information was greater among parents who vaccinated their children (72.4%) than among those who did not (38.0%; p<0.05). The behaviours involved in vaccinating against COVID-19 are multifactorial, and factors such as children’s age, lack of confidence in the efficiency and safety of vaccines, parents’ age, ability to use information appropriately for health decision-making and low ability to recognize fake vaccine-related information are involved in these behaviours.
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Alí M, Ahmed S, Bonna AS, Sarkar AS, Islam MA, Urmi TA, et al. Parental coronavirus disease vaccine hesitancy for children in Bangladesh: a cross-sectional study. F1000 Res. 2022;11:90. https://doi.org/10.12688/f1000research.76181.2
Allan S, Adetifa IMO, Abbas K. Inequities in childhood immunisation coverage associated with socioeconomic, geographic, maternal, child, and place of birth characteristics in Kenya. BMC Infect Dis. 2021;21(1):553. https://doi.org/10.1186/s12879-021-06271-9
Ansolabehere S, Schaffner BF. Does survey mode still matter? Findings from a 2010 multi-mode comparison. Polit Anal. 2014;22(3):285–303. http://www.jstor.org/stable/24573071
Araújo DRD. Como transcrever sua entrevista: técnica de editoração da transcrição de entrevista em pesquisa de abordagem compreensiva. Psico. 2001;32(1):147–57.
Bagateli LE, Saeki EY, Fadda M, Agostoni C, Marchisio P, Milani GP. COVID-19 vaccine hesitancy among parents of children and adolescents living in Brazil. Vaccines. 2021;9(10):1115. https://doi.org/10.3390/vaccines9101115
Bardin L. Análise de conteúdo. Lisboa: Edições 70; 1977. 225 p.
Bertin P, Nera K, Delouvée S. Conspiracy beliefs, rejection of vaccination, and support for hydroxychloroquine: a conceptual replication-extension in the COVID-19 pandemic context. Front Psychol. 2020;11:565128. https://doi.org/10.3389/fpsyg.2020.565128
Boccolini PMM, Boccolini CS, Relvas-Brandt LA, Alves RFS. Dataset on child vaccination in Brazil from 1996 to 2021. Sci Data. 2023;10(1):23. https://doi.org/10.1038/s41597-023-01939-0
Brotas AMP, Costa MCR, Ortiz J, Santos CC, Massarani L. Discurso antivacina no YouTube: a mediação de influenciadores. Rev Eletr Comun Inf Inov Saúde. 2021;15(1):72–92.
Cubizolles C, Barjat T, Chauleur C, Bruel S, Botelho-Nevers E, Gagneux-Brunon A. Evaluation of intentions to get vaccinated against influenza, COVID-19, pertussis and to get a future vaccine against respiratory syncytial virus in pregnant women. Vaccine. 2023;41(49):7342–7. https://doi.org/10.1016/j.vaccine.2023.10.067
Dal Grande E, Chittleborough CR, Campostrini S, Dollard M, Taylor AW. Pre-survey text messages (SMS) improve participation rate in an Australian mobile telephone survey: an experimental study. PLoS One. 2016;11(2):e0150231. https://doi.org/10.1371/journal.pone.015023
Di Giuseppe G, Pelullo CP, Volgare AS, Napolitano F, Pavia M. Parents' willingness to vaccinate their children with COVID-19 vaccine: results of a survey in Italy. J Adolesc Health. 2022;70(4):550–8. https://doi.org/10.1016/j.jadohealth.2022.01.003
Francis AI, Ghany S, Gilkes T, Umakanthan S. Review of COVID-19 vaccine subtypes, efficacy and geographical distributions. Postgrad Med J. 2022;98(1159):389–94. https://doi.org/10.1136/postgradmedj-2021-140654
Galanis P, Vraka I, Siskou O, Konstantakopoulou O, Katsiroumpa A, Kaitelidou D. Willingness, refusal and influential factors of parents to vaccinate their children against the COVID-19: a systematic review and meta-analysis. Prev Med. 2022;157:106994. https://doi.org/10.1016/j.ypmed.2022.106994
García-Toledano E, Palomares-Ruiz A, Cebrián-Martínez A, López-Parra E. Health education and vaccination for the construction of inclusive societies. Vaccines. 2021;9(8):1–15. https://doi.org/10.3390/vaccines9080813
Krieger N, LeBlanc M, Waterman PD, Reisner SL, Testa C, Chen JT. Decreasing survey response rates in the time of COVID-19: implications for analyses of population health and health inequities. Am J Public Health. 2023;113(6):667–70. https://doi.org/10.2105/AJPH.2023.307267
Lavoie K, Gosselin-Boucher V, Stojanovic J, Gupta S, Gagné M, Joyal-Desmarais K, et al. Understanding national trends in COVID-19 vaccine hesitancy in Canada: results from five sequential cross-sectional representative surveys spanning April 2020-March 2021. BMJ Open. 2022;12(4):e059411. https://doi.org/10.1136/bmjopen-2021-059411
Lefèvre F, Lefèvre AMC. O discurso do sujeito coletivo: um novo enfoque em pesquisa qualitativa; desdobramentos. Porto Alegre: EDUCS; 2003.
Li P, Fu JB, Li KF, Liu JN, Wang HL, Liu LJ, et al. Transmission of COVID-19 in the terminal stages of the incubation period: a familial cluster. Int J Infect Dis. 2020;96:452–3. https://doi.org/10.1016/j.ijid.2020.03.027
Maci S. Discourse strategies of fake news in the anti-VAX campaign. Lang Cult Mediat. 2019;6(1):15–43. https://doi.org/10.7358/LCM-2019-001-maci
Maciel ELN, Gomes CC, Almada GL, Medeiros Junior NF, Cardoso OA, Jabor PM, et al. COVID-19 in children, adolescents and young adults: a cross-sectional study in Espírito Santo, Brazil, 2020. Epidemiol Serv Saude. 2021;30(4):e20201029. https://doi.org/10.1590/S1679-49742021000400001
Matos CCS, Tavares JSC, Couto MT. Interface (Botucatu, Online). 2024;28:e230492. https://doi.org/10.1590/interface.230492
Montagni I, Ouazzani-Touhami K, Mebarki A, Texier N, Schück S, Tzourio C, CONFINS group. Acceptance of a COVID-19 vaccine is associated with ability to detect fake news and health literacy. J Public Health (Oxf). 2021;43(4):695–702. https://doi.org/10.1093/pubmed/fdab028
Moscadelli A, Albora G, Biamonte MA, Giorgetti D, Innocenzio M, Paoli S, et al. Fake news and COVID-19 in Italy: results of a quantitative observational study. Int J Environ Res Public Health. 2020;17(16):5850. https://doi.org/10.3390/ijerph17165850
Oliveira T. Desinformação científica em tempos de crise epistêmica: circulação de teorias da conspiração nas plataformas de mídias sociais. Fronteiras Estud Midiáticos. 2020;22(1):21–35. https://doi.org/10.4013/fem.2020.221.03
Organização Pan-Americana da Saúde (OPAS). Desinformação alimenta dúvidas sobre vacinas contra a COVID-19, afirma diretora da OPAS. 2021. Available from: https://www.paho.org/pt/noticias/21-4-2021-desinformacao-alimenta-duvidas-sobre-vacinas-contra-covid-19-afirma-diretora-da
Organização Pan-Americana da Saúde (OPAS). Perguntas frequentes: vacinas contra a COVID-19. 2022. Available from: https://www.paho.org/pt/vacinas-contra-covid-19/perguntas-frequentes-vacinas-contra-covid-19 [Accessed 26 Sep 2022].
Randolph HE, Barreiro LB. Herd immunity: understanding COVID-19. Immunity. 2020;52(5):737–41. https://doi.org/10.1016/j.immuni.2020.04.012
Recuero R, Soares F. O discurso desinformativo sobre a cura do COVID-19 no Twitter: estudo de caso. E-Compós. 2021;24. https://doi.org/10.30962/ec.2127
Recuero R, Stumpf EM. Características do discurso desinformativo no Twitter: estudo do discurso antivacinas da COVID-19. In: Caiado R, Leffa V, editors. Linguagem: tecnologia e ensino. Campinas: Pontes Editores; 2021. p. 111–37.
Recuero R, Volcan T, Jorge FC. Os efeitos da pandemia de COVID-19 no discurso antivacinação infantil no Facebook. Rev Eletr Comun Inf Inov Saúde. 2022;16(4):859-82. https://doi.org/10.29397/reciis.v16i4.3404
Sales F, Souza FC, John VM. O emprego da abordagem DSC (discurso do sujeito coletivo) na pesquisa em educação. Linhas. 2007;8(1):124–45.
Santé Publique France. Covid-19: une enquête pour suivre l'évolution des comportements et de la santé mentale pendant l'épidémie. 2020 [cited 2021 Jan 7]. Available from: https://www.santepubliquefrance.fr/etudes-et-enquetes/coviprev-une-enquete-pour-suivre-l-evolution-des-comportements-et-de-la-sante-mentale-pendant-l-epidemie-de-covid-19 [Accessed 10 Jun 2022].
Seara-Morais GJ, Avelino-Silva TJ, Couto M, Avelino-Silva VI. The pervasive association between political ideology and COVID-19 vaccine uptake in Brazil: an ecologic study. BMC Public Health. 2023;23(1):1606. https://doi.org/10.1186/s12889-023-16409-w
Silveira MM, Conrad NL, Leivas Leite FP. Effect of COVID-19 on vaccination coverage in Brazil. J Med Microbiol. 2021;70(11):10.1099/jmm.0.001466. https://doi.org/10.1099/jmm.0.001466
Skitarelić N, Vidaić M, Skitarelić N. Parents' versus grandparents' attitudes about childhood vaccination. Children (Basel). 2022;9(3):345. https://doi.org/10.3390/children9030345
Souto EP, Fernandez MV, Rosário CA, Petra PC, Matta GC. Hesitação vacinal infantil e COVID-19: uma análise a partir da percepção dos profissionais de saúde. Cad Saude Publica. 2024;40(3):e00061523. https://doi.org/10.1590/0102-311XPT061523
Souto EP, Kabad J. Hesitação vacinal e os desafios para enfrentamento da pandemia de COVID-19 em idosos no Brasil. Rev Bras Geriatr Gerontol. 2020;23(5):e210032. https://doi.org/10.1590/1981-22562020023.210032
Ullah I, Khan KS, Tahir MJ, Ahmed A, Harapan H. Myths and conspiracy theories on vaccines and COVID-19: potential effect on global vaccine refusals. Vacunas. 2021;22(2):93–7. https://doi.org/10.1016/j.vacune.2021.01.009
Wardle C, Derakhshan H. Information disorder: toward an interdisciplinary framework for research and policy making. Council of Europe. 2017;1:1–209.
World Health Organization (WHO). Coronavirus (COVID-19) Dashboard. 2022. Available from: https://covid19.who.int/?adgroupsurvey={adgroupsurvey}&gclid=CjwKCAjwwqaGBhBKEiwAMk-FtCmI8Xh58rZB3V81q18SmmXT4ZX0tuQzABkTLLZY1B1eFdlpF1rNExoC9wsQAvD_BwE [Accessed 9 Jun 2022].
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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
Grant numbers Finance Code 001 -
Fundação de Amparo à Pesquisa e Inovação do Espírito Santo
Grant numbers Grant number 220/2018 -
Conselho Nacional de Desenvolvimento Científico e Tecnológico
Grant numbers Grant number 314722/2021-1