Comparative analysis between osteosarcoma and Ewing's sarcoma: evaluation of the time from onset of signs and symptoms until diagnosis

Authors

  • Raquel Bezerra Guerra University of São Paulo; Faculty of Medicine; Institute of Orthepedics and Traumatology
  • Marcelo Duarte Tostes University of São Paulo; Faculty of Medicine; Institute of Orthepedics and Traumatology
  • Leandro da Costa Miranda University of São Paulo; Faculty of Medicine; Institute of Orthepedics and Traumatology
  • Olavo Pires de Camargo University of São Paulo; Faculty of Medicine; Institute of Orthepedics and Traumatology
  • André Mathias Baptista University of São Paulo; Faculty of Medicine; Institute of Orthepedics and Traumatology
  • Marcelo Tadeu Caiero University of São Paulo; Faculty of Medicine; Institute of Orthepedics and Traumatology
  • Telma Muria dos Santos Machado University of São Paulo; Faculty of Medicine; Institute of Orthepedics and Traumatology
  • Márcia Datz Abadi University of São Paulo; Faculty of Medicine; Institute of Orthepedics and Traumatology
  • Claudia Regina G.C.M Mendes de Oliveira University of São Paulo; Faculty of Medicine; Institute of Orthepedics and Traumatology
  • Renée Zon Filippi University of São Paulo; Faculty of Medicine; Institute of Orthepedics and Traumatology

DOI:

https://doi.org/10.1590/S1807-59322006000200003

Keywords:

Ewing's sarcoma, Osteosarcoma, Bone neoplasias, Chemotherapy, Orthopedic surgery

Abstract

OBJECTIVE: The purposes of this study were to describe the early signs and symptoms of osteosarcoma and Ewing's sarcoma, identify symptoms that could be used to help differentiate the two types of tumors, and determine the time elapsed between the onset of signs and symptoms and the definitive diagnosis in our service, providing information and imputus for earlier diagnosis of these tumors. METHODS: A retrospective analysis of the medical dossiers of 365 patients under 30 years of age diagnosed with osteosarcoma or Ewing's sarcoma was performed, and the aspects of the clinical diagnosis were statistically analyzed and compared. RESULTS: The time between the onset of signs and the symptoms was 5.25 months for osteosarcoma and 8.1 months for Ewing's sarcoma, and the most frequent (89.5%) early symptom of osteosarcoma and Ewing's sarcoma was local pain. Symptoms that might aid diagnosis included early local volume increase and the presence of fever. CONCLUSION: The time until diagnosis of both neoplasias was higher than that reported for North America and Europe. Education of the lay public and medical professionals regarding suspicious early signs and symptoms might shorten the delay of diagnosis.

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Published

2006-04-01

Issue

Section

Original Research

How to Cite

Guerra, R. B., Tostes, M. D., Miranda, L. da C., Camargo, O. P. de, Baptista, A. M., Caiero, M. T., Machado, T. M. dos S., Abadi, M. D., Oliveira, C. R. G. M. de, & Filippi, R. Z. (2006). Comparative analysis between osteosarcoma and Ewing’s sarcoma: evaluation of the time from onset of signs and symptoms until diagnosis . Clinics, 61(2), 99-106. https://doi.org/10.1590/S1807-59322006000200003