Metabolic syndrome patient compliance with drug treatment

Authors

  • Nilcéia Lopes Universidade de São Paulo; Faculdade de Ciências Farmacêuticas; Department of Pharmacy
  • Antonio Carlos Zanini Universidade de São Paulo; Faculdade de Ciências Farmacêuticas; Department of Pharmacy
  • Antonio Casella-Filho Universidade de São Paulo; Faculdade de Medicina; Hospital das Clínicas; Instituto do Coração
  • Antonio Carlos Palandri Chagas Universidade de São Paulo; Faculdade de Medicina; Hospital das Clínicas; Instituto do Coração

DOI:

https://doi.org/10.1590/S1807-59322008000500002

Keywords:

Adherence, Hypertension, Diabetes, Abdominal obesity, Drug utilization

Abstract

OBJECTIVES: 1) To evaluate the compliance with drug treatment in patients with metabolic syndrome. 2) To determine association between access to and use of medicines, as well as the level of knowledge of cardiovascular risk factors and compliance. INTRODUCTION: Low compliance has been one of the greatest challenges for the successful treatment of chronic diseases. Although this issue has been widely studied in patients with isolated hypertension, diabetes and dyslipidemia, compliance studies involving patients with these concomitant diseases or with metabolic syndrome diagnosis are scarce. METHODS: This was a cross-sectional study involving patients who have been diagnosed with metabolic syndrome according to the IDF criteria. Patients were being treated in a Health-Medical School Center bound to the Public Brazilian Healthcare System. This study was conducted in two phases. Phase I was characterized by analyzing medical records and Phase II involved interviewing the patients. A variation of the Morisky-Green Test was used to evaluate compliance. Compliance was the dependent variable and the independent variables included access to medicines, the use of medicines and the level of knowledge concerning cardiovascular risk factors. RESULTS: Two hundred and forty-three patients were identified as being eligible for Phase II, and 75 were included in the study. The average level of compliance was 5.44 points (standard deviation of 0.68), on a scale ranging from 1.00 to 6.00 points. There was no statistically meaningful association between independent variables and compliance. The level of patient knowledge of diet and dyslipidemia was considered to be low. CONCLUSIONS: Patients involved in this study exhibited a high level of compliance with drug treatment. Further research is needed to better elucidate the compliance behavior of patients who have been diagnosed with metabolic syndrome.

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Published

2008-01-01

Issue

Section

Clinical Sciences

How to Cite

Lopes, N., Zanini, A. C., Casella-Filho, A., & Chagas, A. C. P. (2008). Metabolic syndrome patient compliance with drug treatment . Clinics, 63(5), 573-580. https://doi.org/10.1590/S1807-59322008000500002