Restless legs syndrome in subjects with a knee prosthesis: evidence that symptoms are generated in the periphery
DOI:
https://doi.org/10.1590/S1807-59322011001100017Keywords:
Restless Legs Syndrome, RLS pathophysiology, Knee prosthesisAbstract
OBJECTIVE: There are no data adressing the prevalence of restless legs syndrome in subjects who have knee prosthesis. Therefore, we conducted a cross-sectional survey of subjects who underwent knee prosthesis surgery. METHOD: A total of 107 subjects (30 male, 77 female) were interviewed over the telephone regarding restless legs syndrome symptoms. If the patients exhibited symptoms of the syndrome, we conducted face-to-face interviews. Lastly, a therapeutic test with pramipexole was proposed for each subject. RESULTS: In our cohort, 7 males (23%) and 30 females (39%) had restless legs syndrome. Of these, 6 males and 23 females were submitted to face-to-face-interview. Of the males, 5 (83%) had restless legs after the knee surgeryexclusively in the operated leg- and reported no family restless legs history. One man had a prior case of bilateral restless legs syndrome, a positive family history and claimed exacerbation of symptoms in the operated leg. Among the females, 16 (69%) had restless legs prior to surgery. A total of 10 female patients reported bilateral symptoms, with fewer symptoms in the operated leg, while 6 displayed a worse outcome in the operated leg. The 7 females (31%) without restless legs prior to surgery and without a family history experienced symptoms only in the operated leg. All subjects responded favorably to the pramipexole therapeutic test. CONCLUSION: Our results suggest that secondary unilateral restless legs syndrome may ensue from knee prosthesis surgery and that the symptoms are generated in the peripheral nervous system.Downloads
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Published
2011-01-01
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Section
Clinical Sciences
How to Cite
Pereira Júnior, J. C., Silva Neto, J. L. P. da, & Pradella-Hallinan, M. (2011). Restless legs syndrome in subjects with a knee prosthesis: evidence that symptoms are generated in the periphery . Clinics, 66(11), 1955-1959. https://doi.org/10.1590/S1807-59322011001100017