Design and baseline characteristics of a coronary heart disease prospective cohort: two-year experience from the strategy of registry of acute coronary syndrome study (ERICO study)

Authors

  • Alessandra C. Goulart Universidade de São Paulo; Faculdade de Medicina
  • Itamar S. Santos Universidade de São Paulo; Faculdade de Medicina
  • Debora Sitnik Universidade de São Paulo; Hospital Universitário; Center for Clinical and Epidemiological Research
  • Henrique L. Staniak Universidade de São Paulo; Hospital Universitário; Center for Clinical and Epidemiological Research
  • Ligia M. Fedeli Universidade de São Paulo; Hospital Universitário; Center for Clinical and Epidemiological Research
  • Carlos Alberto Pastore Universidade de São Paulo; Hospital das Clínicas; Instituto do Coração
  • Nelson Samesima Universidade de São Paulo; Hospital das Clínicas; Instituto do Coração
  • Marcio S. Bittencourt Universidade de São Paulo; Hospital das Clínicas; Instituto do Coração
  • Alexandre C. Pereira Universidade de São Paulo; Hospital das Clínicas; Instituto do Coração
  • Paulo A. Lotufo Universidade de São Paulo; Faculdade de Medicina
  • Isabela M. Bensenor Universidade de São Paulo; Faculdade de Medicina

DOI:

https://doi.org/10.1590/clin.v68i3.72148

Keywords:

Coronary Acute Syndrome, Epidemiology, Registries

Abstract

OBJECTIVES: To describe the ERICO study (Strategy of Registry of Acute Coronary Syndrome), a prospective cohort to investigate the epidemiology of acute coronary syndrome. METHODS: The ERICO study, which is being performed at a secondary general hospital in São Paulo, Brazil, is enrolling consecutive acute coronary syndrome patients who are 35 years old or older. The sociodemographic information, medical assessments, treatment data and blood samples are collected at admission. After 30 days, the medical history is updated, and additional blood and urinary samples are collected. In addition, a retinography, carotid intima-media thickness, heart rate variability and pulse-wave velocity are performed. Questionnaires about food frequency, physical activity, sleep apnea and depression are also applied. At six months and annually after an acute event, information is collected by telephone. RESULTS: From February 2009 to September 2011, 738 patients with a diagnosis of an acute coronary syndrome were enrolled. Of these, 208 (28.2%) had ST-elevation myocardial infarction (STEMI), 288 (39.0%) had non-ST-elevation myocardial infarction (NSTEMI) and 242 (32.8%) had unstable angina (UA). The mean age was 62.7 years, 58.5% were men and 77.4% had 8 years or less of education. The most common cardiovascular risk factors were hypertension (76%) and sedentarism (73.4%). Only 29.2% had a prior history of coronary heart disease. Compared with the ST-elevation myocardial infarction subgroup, the unstable angina and non-ST-elevation myocardial infarction patients had higher frequencies of hypertension, diabetes, prior coronary heart disease (p<0.001) and dyslipidemia (p = 0.03). Smoking was more frequent in the ST-elevation myocardial infarction patients (p = 0.006). CONCLUSIONS: Compared with other hospital registries, our findings revealed a higher burden of CV risk factors and less frequent prior CHD history.

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Published

2013-01-01

Issue

Section

Rapid Communication

How to Cite

Goulart, A. C., Santos, I. S., Sitnik, D., Staniak, H. L., Fedeli, L. M., Pastore, C. A., Samesima, N., Bittencourt, M. S., Pereira, A. C., Lotufo, P. A., & Bensenor, I. M. (2013). Design and baseline characteristics of a coronary heart disease prospective cohort: two-year experience from the strategy of registry of acute coronary syndrome study (ERICO study). Clinics, 68(3), 431-434. https://doi.org/10.1590/clin.v68i3.72148